14,15-Dihydroxy-5,8,10,12-eicosatetraenoic acid

Base Information

Chemical Name:14,15-Dihydroxy-5,8,10,12-eicosatetraenoic acid
CAS No.:77667-09-5
Molecular Formula:C₂₀H₃₂O₄
Molecular Weight:336.472
Hs Code.:
Metabolomics Workbench ID:2698
Mol file:77667-09-5.mol

Synonyms:14,15-dihydroxy-5,8,10,12-eicosatetraenoic acid;14,15-leukotriene B(4);14,15-leukotriene B4;14,15-leukotriene B4, (S-(R*,R*-(E,E,Z,Z)))-isomer;14,15-leukotriene B4, (S-(R*,S*-(E,E,Z,Z)))-isomer;14,15-LTB4

Suppliers and Price of 14,15-Dihydroxy-5,8,10,12-eicosatetraenoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 14,15-Dihydroxy-5,8,10,12-eicosatetraenoic acid

Chemical Property:

Vapor Pressure:8.43E-14mmHg at 25°C
Boiling Point:537.6°C at 760 mmHg
Flash Point:293°C
PSA：77.76000
Density:1.04g/cm³
LogP:4.38230
XLogP3:4.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:14
Exact Mass:336.23005950
Heavy Atom Count:24
Complexity:421

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCC(C(C=CC=CC=CCC=CCCCC(=O)O)O)O
Isomeric SMILES:CCCCCC(C(/C=C/C=C/C=C/C/C=C/CCCC(=O)O)O)O

Technology Process of 14,15-Dihydroxy-5,8,10,12-eicosatetraenoic acid

There total 43 articles about 14,15-Dihydroxy-5,8,10,12-eicosatetraenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: methyl (5Z,8Z,10E,12E,14R,15S)-14,15-dihydroxyicosa-5,8,10,12-tetraenoate

: 82263-61-4,77667-09-5
(5Z,8Z,10E,12E,14R,15S)-14,15-dihydroxyicosa-5,8,10,12-tetraenoic acid

Guidance literature:: With lithium hydroxide monohydrate; In methanol; water; at 20 ℃; for 1h;
DOI:10.1039/c8ob02116c

Reference yield: 58.0%

: 98718-84-4
(5Z,8Z,11Z)-12-[(2R,3R)-3-((S)-1-Hydroxy-hexyl)-oxiranyl]-dodeca-5,8,11-trienoic acid

: 82263-60-3,77667-09-5
14(S),15(S)-dihydroxy 5,8-Z,10,12-E-eicosatetraenoic acid

Guidance literature:: With lithium hexamethyldisilazane; In tetrahydrofuran; 0 to 23 deg C over 1 h, 3 h at 23 deg C;
DOI:10.1016/S0040-4039(00)98341-2