2-(p-tolyl)-3-(p-tolylethynyl)quinoxaline

Base Information

• Chemical Name: 2-(p-tolyl)-3-(p-tolylethynyl)quinoxaline
• CAS No.: 1319039-10-5
• Molecular Formula: C₂₄H₁₈N₂
• Molecular Weight: 334.42
• Mol file: 1319039-10-5.mol

Synonyms:2-(p-tolyl)-3-(p-tolylethynyl)quinoxaline

Chemical Property of 2-(p-tolyl)-3-(p-tolylethynyl)quinoxaline

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 2-(p-tolyl)-3-(p-tolylethynyl)quinoxaline

There total 5 articles about 2-(p-tolyl)-3-(p-tolylethynyl)quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,2-diamino-benzene (95-54-5) + 4-n-methylphenylacetylene (766-97-2) → 2-(p-tolyl)-3-(p-tolylethynyl)quinoxaline (1319039-10-5)

Guidance literature:

With copper diacetate; caesium carbonate; In ethanol; water; at 0 - 80 ℃; for 2h; regioselective reaction; Green chemistry;

DOI:10.1002/aoc.5188

Reference yield: 85.0%

2-chloro-3-(p-tolylethynyl)quinoxaline (1407513-26-1) + 4-methylphenylboronic acid (5720-05-8) → 2-(p-tolyl)-3-(p-tolylethynyl)quinoxaline (1319039-10-5)

Guidance literature:

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; Inert atmosphere; Reflux;

DOI:10.1002/ejoc.201600660

Reference yield:

phenylacetylene (536-74-3) + 1,2-diamino-benzene (95-54-5) + 4-n-methylphenylacetylene (766-97-2) → 1,4-diphenyl-1,3-butadiyne (886-66-8) + 2-(p-tolyl)-3-(p-tolylethynyl)quinoxaline (1319039-10-5)

Guidance literature:

With copper diacetate; caesium carbonate; In ethanol; water; at 80 ℃; Overall yield = 95percent;

DOI:10.1002/aoc.5188

upstream raw materials:

1,2-diamino-benzene

4-n-methylphenylacetylene

2-chloro-3-(p-tolylethynyl)quinoxaline

4-methylphenylboronic acid