1L-(1R)-(1,3,4/2)-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-methylene-1,2,3-cyclohexanetriol

Base Information

Chemical Name:1L-(1R)-(1,3,4/2)-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-methylene-1,2,3-cyclohexanetriol
CAS No.:85240-29-5
Molecular Formula:C₂₁H₂₅NO₈
Molecular Weight:419.431
Hs Code.:

Synonyms:1L-(1R)-(1,3,4/2)-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-methylene-1,2,3-cyclohexanetriol

Suppliers and Price of 1L-(1R)-(1,3,4/2)-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-methylene-1,2,3-cyclohexanetriol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1L-(1R)-(1,3,4/2)-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-methylene-1,2,3-cyclohexanetriol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1L-(1R)-(1,3,4/2)-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-methylene-1,2,3-cyclohexanetriol

There total 7 articles about 1L-(1R)-(1,3,4/2)-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-methylene-1,2,3-cyclohexanetriol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

: 85240-28-4
1L-(1,3,4/2,6)-1,2,3-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-C-(iodomethyl)-1,2,3-cyclohexanetriol

: 85240-29-5
1L-(1R)-(1,3,4/2)-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-methylene-1,2,3-cyclohexanetriol

Guidance literature:: With 1,8-diazabicyclo[5.4.0]undec-7-ene; In N,N-dimethyl-formamide; at 40 - 50 ℃; for 2h; Reagent/catalyst; Solvent; Temperature;

Reference yield:

: 32780-32-8
validamine

: 85240-29-5
1L-(1R)-(1,3,4/2)-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-methylene-1,2,3-cyclohexanetriol

Guidance literature:: Multi-step reaction with 5 steps

1: 31.8 g / H₂O; dioxane / 1.) 0-5 deg C, 1 h, 2.) room temp., 1 h

2: 5.1 g / pyridine / 15 h / Ambient temperature

3: 26.2 g / pyridine / 16 h / Ambient temperature

4: 16.9 g / sodium iodide / acetic anhydride / 0.5 h / 120 - 130 °C

5: 11.6 g / silver fluoride / pyridine / 3.5 h / 20 - 25 °C

With silver fluoride; sodium iodide; In 1,4-dioxane; pyridine; water; acetic anhydride;
DOI:10.1016/0008-6215(85)85122-3

Reference yield:

: 85281-05-6
N-(benzyloxycarbonyl)validamine

: 85240-29-5
1L-(1R)-(1,3,4/2)-tri-O-acetyl-4-<(benzyloxycarbonyl)amino>-6-methylene-1,2,3-cyclohexanetriol

Guidance literature:: Multi-step reaction with 4 steps

1: 5.1 g / pyridine / 15 h / Ambient temperature

2: 26.2 g / pyridine / 16 h / Ambient temperature

3: 16.9 g / sodium iodide / acetic anhydride / 0.5 h / 120 - 130 °C

4: 11.6 g / silver fluoride / pyridine / 3.5 h / 20 - 25 °C

With silver fluoride; sodium iodide; In pyridine; acetic anhydride;
DOI:10.1016/0008-6215(85)85122-3