Technology Process of 3,5-diphenyl-8-(2-furyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
There total 4 articles about 3,5-diphenyl-8-(2-furyl)-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Na2CO3; Pd(P(C6H5)3)4;
In
tetrahydrofuran; water; toluene;
under N2 (OC4H3)C9H4N2Br2BF2, PhB(OH)2 and Na2CO3 in water/THF/toluene (1:1:1) stirred for 5 min, Pd(PPh3)4 added, refluxed at 80 °C; TLC, diluted with water, extd. wiyj diethyl ether, washed with water, brine, dried over MgSO4, evapd., purified on silica gel (petroleum ether/ethyl acetate);
DOI:10.1016/j.ica.2011.11.017
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 2,3-dichloro-5,6-dicyano-1,4-benzoquinone / dichloromethane; triethylamine
2: Na2CO3; Pd(P(C6H5)3)4 / toluene; tetrahydrofuran; water
With
2,3-dichloro-5,6-dicyano-1,4-benzoquinone; Na2CO3; Pd(P(C6H5)3)4;
In
tetrahydrofuran; dichloromethane; water; triethylamine; toluene;
DOI:10.1016/j.ica.2011.11.017
- Guidance literature:
-
Multi-step reaction with 4 steps
1: boron trifluoride diethyl etherate / dichloromethane / 0.25 h / 20 °C
2: N-Bromosuccinimide / tetrahydrofuran
3: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane
4: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / tetrahydrofuran; water; toluene / 80 °C / Inert atmosphere
With
N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium(0); boron trifluoride diethyl etherate; sodium carbonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone;
In
tetrahydrofuran; dichloromethane; water; toluene;
DOI:10.1016/j.ica.2011.11.017
