Technology Process of (2R,3aR,4R,6R,6aS)-4-Benzyloxy-6-methyl-2-phenyl-tetrahydro-cyclopenta[1,3]dioxole
There total 10 articles about (2R,3aR,4R,6R,6aS)-4-Benzyloxy-6-methyl-2-phenyl-tetrahydro-cyclopenta[1,3]dioxole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 96 percent / TsOH
2: 81 percent / K2CO3 / methanol
3: 97 percent / Et3N
4: 87 percent / n-Bu4NF
5: 74 percent / Swern's reagent
6: 79 percent / CuI, BF3*Et2O
7: 96 percent / L-Selectride
8: 87 percent / NaI, NaH
With
copper(l) iodide; Swern's reagent; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; L-Selectride; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; triethylamine; sodium iodide;
In
methanol;
DOI:10.1246/cl.1993.1503
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 97 percent / imidazole
2: 94 percent / OsO4, N-methylmorpholine N-oxide monohydrate (NMO)
3: 96 percent / TsOH
4: 81 percent / K2CO3 / methanol
5: 97 percent / Et3N
6: 87 percent / n-Bu4NF
7: 74 percent / Swern's reagent
8: 79 percent / CuI, BF3*Et2O
9: 96 percent / L-Selectride
10: 87 percent / NaI, NaH
With
1H-imidazole; copper(l) iodide; osmium(VIII) oxide; Swern's reagent; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; L-Selectride; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; 4-methylmorpholine N-oxide; triethylamine; sodium iodide;
In
methanol;
DOI:10.1246/cl.1993.1503
