dipropargylacetic acid

Base Information

• Chemical Name: dipropargylacetic acid
• CAS No.: 65994-70-9
• Molecular Formula: C₈H₈O₂
• Molecular Weight: 136.15
• Mol file: 65994-70-9.mol

Synonyms:dipropargylacetic acid

Chemical Property of dipropargylacetic acid

Chemical Property:

Purity/Quality:

98%, ^*data from raw suppliers

2-(prop-2-yn-1-yl)pent-4-ynoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dipropargylacetic acid

There total 12 articles about dipropargylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl 2-(prop-2-yn-1-yl)pent-4-ynoate (181478-00-2) → dipropargylacetic acid (65994-70-9)

Guidance literature:

With sodium hydroxide; In ethanol; at 20 ℃; for 64h; Reflux;

Reference yield: 82.0%

C9H8O2 → dipropargylacetic acid (65994-70-9)

Guidance literature:

With camphor-10-sulfonic acid; dihydrogen peroxide; In ethyl acetate; at 20 ℃; for 1h;

DOI:10.1039/c4ra11237g

Reference yield: 79.9%

2,2-di(prop-2-ynyl)propan-1,3-dioic acid (4431-32-7) → dipropargylacetic acid (65994-70-9)

Guidance literature:

at 135 ℃;

upstream raw materials:

2,2-di(prop-2-ynyl)propan-1,3-dioic acid

ethyl acetoacetate

propargyl bromide

allyl-prop-2-ynyl-malonic acid

Downstream raw materials:

3-methyl-5-oxo-3-cyclohexene-1-carboxylic acid

m-Toluic acid

N,N-diphenyl-N'-(2-(2-propinyl)-4-pentinoyl)thiourea

N-benzyl-N'-(2-(2-propinyl)-4-pentinoyl)thiourea

Refernces

• 1、 Ali, Tammar Hussein,Heidelberg, Thorsten,Hussen, Rusnah Syahila Duali. "Base-induced cyclization of derivatives of bispropargylated acetic acid to m -toluic acid". . p. 1361 - 1364. Retrieved 2015/06/16.
• 2、 Yu, Xin,Liu, Zheng,Xia, Zilei,Shen, Zhigao,Pan, Xixian,Zhang, Hui,Xie, Weiqing. "Oxidative rearrangement of malondialdehyde: Substrate scope and mechanistic insights". . p. 53397 - 53401. Retrieved 2015/01/16.