(3,7b-dihydro-2H-1,1a-diazacyclopropa[a]naphthalen-1-yl)-p-tolylmethanone

Base Information

• Chemical Name: (3,7b-dihydro-2H-1,1a-diazacyclopropa[a]naphthalen-1-yl)-p-tolylmethanone
• CAS No.: 1006061-05-7
• Molecular Formula: C₁₇H₁₆N₂O
• Molecular Weight: 264.327
• Mol file: 1006061-05-7.mol

Synonyms:(3,7b-dihydro-2H-1,1a-diazacyclopropa[a]naphthalen-1-yl)-p-tolylmethanone

Chemical Property of (3,7b-dihydro-2H-1,1a-diazacyclopropa[a]naphthalen-1-yl)-p-tolylmethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3,7b-dihydro-2H-1,1a-diazacyclopropa[a]naphthalen-1-yl)-p-tolylmethanone

There total 1 articles about (3,7b-dihydro-2H-1,1a-diazacyclopropa[a]naphthalen-1-yl)-p-tolylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

4-methyl-benzoyl chloride (874-60-2) + 1,2,3,7b-tetrahydro-1,1a-diazacyclopropa[α]naphthalene (92658-37-2) → (3,7b-dihydro-2H-1,1a-diazacyclopropa[a]naphthalen-1-yl)-p-tolylmethanone (1006061-05-7)

Guidance literature:

With pyridine; In benzene; at 50 - 55 ℃; for 0.5h;

DOI:10.1055/s-2007-990888

Reference yield:

(3,7b-dihydro-2H-1,1a-diazacyclopropa[a]naphthalen-1-yl)-p-tolylmethanone (1006061-05-7) + 4-tert-Butylphenylacetylene (772-38-3) → 2-(4-(tert-butyl)phenyl)-5,6-dihydropyrazolo[5,1-a]isoquinoline + C29H30N2O

Guidance literature:

With air; In chloroform; at 50 ℃; for 24h; under 760.051 Torr; Title compound not separated from byproducts.;

DOI:10.1055/s-2007-990888

Reference yield:

4-bromo-1-ethynylbenzene (766-96-1) + (3,7b-dihydro-2H-1,1a-diazacyclopropa[a]naphthalen-1-yl)-p-tolylmethanone (1006061-05-7) → C25H21BrN2O

Guidance literature:

With air; In dichloromethane; at 50 ℃; for 24h;

DOI:10.1055/s-2007-990888

upstream raw materials:

4-methyl-benzoyl chloride

1,2,3,7b-tetrahydro-1,1a-diazacyclopropa[α]naphthalene

Downstream raw materials:

2-(4-fluorophenyl)-5,6-dihydropyrazolo[5,1-a]isoquinoline

2-(o-tolyl)-5,6-dihydropyrazolo[5,1-a]isoquinoline

(2-phenyl-6,10b-dihydro-5H-pyrazolo[5,1-a]isoquinolin-3-yl)-p-tolylmethanone

2-phenyl-5,6-dihydro-pyrazolo<5,1-a>isoquinoline