Bis({[3-(trifluoromethyl)phenyl]methyl})amine

Base Information

• Chemical Name: Bis({[3-(trifluoromethyl)phenyl]methyl})amine
• CAS No.: 863763-65-9
• Molecular Formula: C₁₆H₁₃F₆N
• Molecular Weight: 333.276
• DSSTox Substance ID: DTXSID801142950
• Mol file: 863763-65-9.mol

Synonyms:bis({[3-(trifluoromethyl)phenyl]methyl})amine;863763-65-9;1-[3-(trifluoromethyl)phenyl]-N-[[3-(trifluoromethyl)phenyl]methyl]methanamine;N,N-bis[3-(trifluoromethyl)benzyl]amine;SCHEMBL4239980;SHPHDCSCFBKTES-UHFFFAOYSA-N;DTXSID801142950;AKOS001106063;NCGC00337667-01;CS-0234553;EN300-14304;AB01329118-02;Z86153370;3-(Trifluoromethyl)-N-[[3-(trifluoromethyl)phenyl]methyl]benzenemethanamine

Chemical Property of Bis({[3-(trifluoromethyl)phenyl]methyl})amine

Chemical Property:

• XLogP3: 4.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 333.09521839
• Heavy Atom Count: 23
• Complexity: 331

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)C(F)(F)F)CNCC2=CC(=CC=C2)C(F)(F)F

Technology Process of Bis({[3-(trifluoromethyl)phenyl]methyl})amine

There total 1 articles about Bis({[3-(trifluoromethyl)phenyl]methyl})amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

3-(TRIFLUOROMETHYL)BENZYLAMINE (2740-83-2) + 3-Trifluoromethylbenzaldehyde (454-89-7) → bis(3-(trifluoromethyl)benzyl)amine (863763-65-9)

Guidance literature:

With sodium tris(acetoxy)borohydride; acetic acid; In 1,2-dichloro-ethane; at 20 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.5b03194

Reference yield: 91.0%

bis(3-(trifluoromethyl)benzyl)amine (863763-65-9) → N-(3-(trifluoromethyl)benzyl)-1-(3-(trifluoromethyl)phenyl)methanimine (946495-09-6)

Guidance literature:

With oxygen; [5,6]fullerene-C₇₀; In chloroform; toluene; for 20h; Molecular sieve; Irradiation;

DOI:10.1021/acs.orglett.5b03194

upstream raw materials:

3-(TRIFLUOROMETHYL)BENZYLAMINE

3-Trifluoromethylbenzaldehyde

Downstream raw materials:

N-(3-(trifluoromethyl)benzyl)-1-(3-(trifluoromethyl)phenyl)methanimine