p-fluorocinnamoyl-CoA

Base Information

• Chemical Name: p-fluorocinnamoyl-CoA
• CAS No.: 143246-49-5
• Molecular Formula: C₃₀H₄₁FN₇O₁₇P₃S
• Molecular Weight: 915.678
• Mol file: 143246-49-5.mol

Synonyms:p-fluorocinnamoyl-CoA

Chemical Property of p-fluorocinnamoyl-CoA

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of p-fluorocinnamoyl-CoA

There total 1 articles about p-fluorocinnamoyl-CoA which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-fluorocinnamic acid (459-32-5,14290-66-5,14290-86-9) + coenzyme A (85-61-0) → p-fluorocinnamoyl-CoA (143246-49-5)

Guidance literature:

With 4-coumarate-CoA ligase from nicotiana tabacum; ATP; magnesium chloride; at 25 ℃; for 24h; pH=8; Reagent/catalyst; Kinetics; aq. buffer; Enzymatic reaction;

DOI:10.1021/bi300425j

Reference yield: 26.0%

p-fluorocinnamoyl-CoA (143246-49-5) + S-(hydrogen malonyl)coenzyme A (524-14-1) → C19H14F2O2 (615563-94-5)

Guidance literature:

With Huperzia serrata type III polyketide synthase; In aq. phosphate buffer; at 37 ℃; for 12h; pH=7; Enzymatic reaction;

DOI:10.1021/acs.orglett.6b01501

Reference yield:

β-ketodecanoic acid (13283-92-6) + p-fluorocinnamoyl-CoA (143246-49-5) + S-(hydrogen malonyl)coenzyme A (524-14-1) → C18H23FO2

Guidance literature:

With Huperzia serrata type III polyketide synthase; In aq. phosphate buffer; dimethyl sulfoxide; at 37 ℃; for 12h; pH=7; Enzymatic reaction;

DOI:10.1021/acs.orglett.6b01501

upstream raw materials:

4-fluorocinnamic acid

coenzyme A

Downstream raw materials:

C₁₉H₁₄F₂O₂