Technology Process of 8-benzyloxy-1-hydroxy-4,4-dimethyl-2-octene
There total 5 articles about 8-benzyloxy-1-hydroxy-4,4-dimethyl-2-octene which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
tetrahydrofuran; methanol;
for 5h;
Ambient temperature;
DOI:10.1248/cpb.43.607
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 58 percent / pyridine / Ambient temperature
2: 54 percent / pyridinium chlorochromate, celite, AcONa / CH2Cl2 / Ambient temperature
3: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 45 min, 2.) THF, hexane, RT, overnight
4: 81 percent / p-TsOH / methanol; tetrahydrofuran / 5 h / Ambient temperature
With
pyridine; n-butyllithium; Celite; sodium acetate; toluene-4-sulfonic acid; pyridinium chlorochromate;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1248/cpb.43.607
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 100 percent / LiAlH4 / tetrahydrofuran / 2 h / Ambient temperature
2: 58 percent / pyridine / Ambient temperature
3: 54 percent / pyridinium chlorochromate, celite, AcONa / CH2Cl2 / Ambient temperature
4: 1.) n-BuLi / 1.) THF, hexane, 0 deg C, 45 min, 2.) THF, hexane, RT, overnight
5: 81 percent / p-TsOH / methanol; tetrahydrofuran / 5 h / Ambient temperature
With
pyridine; lithium aluminium tetrahydride; n-butyllithium; Celite; sodium acetate; toluene-4-sulfonic acid; pyridinium chlorochromate;
In
tetrahydrofuran; methanol; dichloromethane;
DOI:10.1248/cpb.43.607
