1-{3-(4-Carbamimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide

Base Information

Chemical Name:1-{3-(4-Carbamimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide
CAS No.:118964-82-2
Molecular Formula:C₂₇H₂₉N₅O₆S*HI
Molecular Weight:679.536
Hs Code.:

Synonyms:1-{3-(4-Carbamimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide

Suppliers and Price of 1-{3-(4-Carbamimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-{3-(4-Carbamimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-{3-(4-Carbamimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide

There total 4 articles about 1-{3-(4-Carbamimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 118964-77-5
1-{3-(4-Methylsulfanylcarbonimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide

: 118964-82-2
1-{3-(4-Carbamimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide

Guidance literature:: With ammonium acetate; In methanol; at 60 ℃; for 3h;

Reference yield:

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 118964-82-2
1-{3-(4-Carbamimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) 4-ethylmorpholine, isobutyl chloroformate; 2.) 4-ethylmorpholine / 1.) CHCl₃, 0 deg C, 15 min 2.) CHCl₃, 0 deg C, 30 min, then 60 min, room temperature

2: H₂S, TEA / pyridine / 72 h / Ambient temperature

3: 60 percent / acetone / 0.17 h / Heating

4: 60 percent / CH₃COONH₄ / methanol / 3 h / 60 °C

With N-ethylmorpholine;; TEA; hydrogen sulfide; ammonium acetate; isobutyl chloroformate; In pyridine; methanol; acetone;

Reference yield:

: 92771-15-8
3-(4-Cyano-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionic acid

: 118964-82-2
1-{3-(4-Carbamimidoyl-phenyl)-2-[2-(naphthalene-1-sulfonylamino)-acetylamino]-propionyl}-pyrrolidine-2-carboxylic acid; hydriodide

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) 4-ethylmorpholine, isobutyl chloroformate; 2.) 4-ethylmorpholine / 1.) CHCl₃, 0 deg C, 15 min 2.) CHCl₃, 0 deg C, 30 min, then 60 min, room temperature

2: H₂S, TEA / pyridine / 72 h / Ambient temperature

3: 60 percent / acetone / 0.17 h / Heating

4: 60 percent / CH₃COONH₄ / methanol / 3 h / 60 °C

With N-ethylmorpholine;; TEA; hydrogen sulfide; ammonium acetate; isobutyl chloroformate; In pyridine; methanol; acetone;