4-amino-N-[{4-((1-carbamoyl-4-piperidinyl)methyl)-2-morpholinyl}methyl]-5-chloro-2-ethoxybenzamide

Base Information

Chemical Name:4-amino-N-[{4-((1-carbamoyl-4-piperidinyl)methyl)-2-morpholinyl}methyl]-5-chloro-2-ethoxybenzamide
CAS No.:1184659-09-3
Molecular Formula:C₂₁H₃₂ClN₅O₄
Molecular Weight:453.969
Hs Code.:

Synonyms:4-amino-N-[{4-((1-carbamoyl-4-piperidinyl)methyl)-2-morpholinyl}methyl]-5-chloro-2-ethoxybenzamide

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Chemical Property of 4-amino-N-[{4-((1-carbamoyl-4-piperidinyl)methyl)-2-morpholinyl}methyl]-5-chloro-2-ethoxybenzamide

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Technology Process of 4-amino-N-[{4-((1-carbamoyl-4-piperidinyl)methyl)-2-morpholinyl}methyl]-5-chloro-2-ethoxybenzamide

There total 2 articles about 4-amino-N-[{4-((1-carbamoyl-4-piperidinyl)methyl)-2-morpholinyl}methyl]-5-chloro-2-ethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1118-02-1
trimethylsilyl isocyanate

: 1184658-86-3
4-amino-5-chloro-2-ethoxy-N-[[4-(4-piperidinylmethyl)-2-morpholinyl]methyl]-benzamide

: 1184659-09-3
4-amino-N-[{4-((1-carbamoyl-4-piperidinyl)methyl)-2-morpholinyl}methyl]-5-chloro-2-ethoxybenzamide

Guidance literature:: trimethylsilyl isocyanate; 4-amino-5-chloro-2-ethoxy-N-[[4-(4-piperidinylmethyl)-2-morpholinyl]methyl]-benzamide; In dichloromethane; at 20 ℃; for 2.5h;

With water;

Reference yield:

: 1184662-46-1
2-aminomethyl-4-[(1-carbamoyl-4-piperidinyl)methyl]morpholine

: 108282-38-8
4-amino-5-chloro-2-ethoxybenzoic acid

: 1184659-09-3
4-amino-N-[{4-((1-carbamoyl-4-piperidinyl)methyl)-2-morpholinyl}methyl]-5-chloro-2-ethoxybenzamide

Guidance literature:: 4-amino-5-chloro-2-ethoxybenzoic acid; With 1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

2-aminomethyl-4-[(1-carbamoyl-4-piperidinyl)methyl]morpholine; In N,N-dimethyl-formamide; at 20 ℃;