Technology Process of <α-2H2>benzyl isolongifolyl thioether
There total 7 articles about <α-2H2>benzyl isolongifolyl thioether which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 84 percent / LiAlD4 / diethyl ether / 3 h / 20 °C
2: 90 percent / thionyl chloride, pyridine / CH2Cl2 / 12 h / 20 °C
3: thiourea / dioxane / 3 h / Heating
4: aq. NaOH / dioxane / 3 h / Heating
5: 5.04 g / NaOMe / methanol; hexamethylphosphoric acid triamide / 42 h / Heating
With
pyridine; sodium hydroxide; thionyl chloride; lithium aluminium deuteride; sodium methylate; thiourea;
In
1,4-dioxane; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; diethyl ether; dichloromethane;
DOI:10.1021/jo00136a014
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 90 percent / thionyl chloride, pyridine / CH2Cl2 / 12 h / 20 °C
2: thiourea / dioxane / 3 h / Heating
3: aq. NaOH / dioxane / 3 h / Heating
4: 5.04 g / NaOMe / methanol; hexamethylphosphoric acid triamide / 42 h / Heating
With
pyridine; sodium hydroxide; thionyl chloride; sodium methylate; thiourea;
In
1,4-dioxane; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide; dichloromethane;
DOI:10.1021/jo00136a014
- Guidance literature:
-
Multi-step reaction with 3 steps
1: thiourea / dioxane / 3 h / Heating
2: aq. NaOH / dioxane / 3 h / Heating
3: 5.04 g / NaOMe / methanol; hexamethylphosphoric acid triamide / 42 h / Heating
With
sodium hydroxide; sodium methylate; thiourea;
In
1,4-dioxane; methanol; N,N,N,N,N,N-hexamethylphosphoric triamide;
DOI:10.1021/jo00136a014
