tert-butyl (1R,2R)-2-((S)-1-hydroxy-3-phenylpropan-2-ylcarbamoyl)-1-(4-methoxyphenyl)pentylcarbamate

Base Information

Chemical Name:tert-butyl (1R,2R)-2-((S)-1-hydroxy-3-phenylpropan-2-ylcarbamoyl)-1-(4-methoxyphenyl)pentylcarbamate
CAS No.:1200722-87-7
Molecular Formula:C₂₇H₃₈N₂O₅
Molecular Weight:470.609
Hs Code.:

Synonyms:tert-butyl (1R,2R)-2-((S)-1-hydroxy-3-phenylpropan-2-ylcarbamoyl)-1-(4-methoxyphenyl)pentylcarbamate

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Chemical Property of tert-butyl (1R,2R)-2-((S)-1-hydroxy-3-phenylpropan-2-ylcarbamoyl)-1-(4-methoxyphenyl)pentylcarbamate

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Technology Process of tert-butyl (1R,2R)-2-((S)-1-hydroxy-3-phenylpropan-2-ylcarbamoyl)-1-(4-methoxyphenyl)pentylcarbamate

There total 1 articles about tert-butyl (1R,2R)-2-((S)-1-hydroxy-3-phenylpropan-2-ylcarbamoyl)-1-(4-methoxyphenyl)pentylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1200722-29-7
tert-butyl (1R,2R)-2-((S)-4-benzyl-2-oxooxazolidine-3-carbonyl)-1-(4-methoxyphenyl)pentylcarbamate

: 1200722-87-7
tert-butyl (1R,2R)-2-((S)-1-hydroxy-3-phenylpropan-2-ylcarbamoyl)-1-(4-methoxyphenyl)pentylcarbamate

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 0 - 20 ℃; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tet.2009.09.072

Reference yield: 83.0%

: 1200722-87-7
tert-butyl (1R,2R)-2-((S)-1-hydroxy-3-phenylpropan-2-ylcarbamoyl)-1-(4-methoxyphenyl)pentylcarbamate

: 1200722-99-1
tert-butyl (1R,2R)-1-(4-methoxyphenyl)-2-((S)-1-oxo-3-phenylpropan-2-ylcarbamoyl)pentylcarbamate

Guidance literature:: With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In dimethyl sulfoxide; at 20 ℃; for 8h; Inert atmosphere;
DOI:10.1016/j.tet.2009.09.072