[3-dodecyloxy-5-(2-{2-[2-(2-{methyl-[4-(4-nitrophenylazo)phenyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)phenyl]methanol

Base Information

• Chemical Name: [3-dodecyloxy-5-(2-{2-[2-(2-{methyl-[4-(4-nitrophenylazo)phenyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)phenyl]methanol
• CAS No.: 1447828-68-3
• Molecular Formula: C₄₀H₅₈N₄O₈
• Molecular Weight: 722.923
• Mol file: 1447828-68-3.mol

Synonyms:[3-dodecyloxy-5-(2-{2-[2-(2-{methyl-[4-(4-nitrophenylazo)phenyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)phenyl]methanol

Chemical Property of [3-dodecyloxy-5-(2-{2-[2-(2-{methyl-[4-(4-nitrophenylazo)phenyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)phenyl]methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [3-dodecyloxy-5-(2-{2-[2-(2-{methyl-[4-(4-nitrophenylazo)phenyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)phenyl]methanol

There total 4 articles about [3-dodecyloxy-5-(2-{2-[2-(2-{methyl-[4-(4-nitrophenylazo)phenyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)phenyl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

3-dodecyloxy-5-hydroxybenzyl alcohol (912815-49-7) + (2-{2-[2-(2-iodoethoxy)ethoxy]ethoxy}ethyl)methyl-[4-(4-nitro-phenylazo)phenyl]amine → [3-dodecyloxy-5-(2-{2-[2-(2-{methyl-[4-(4-nitrophenylazo)phenyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)phenyl]methanol (1447828-68-3)

Guidance literature:

With 18-crown-6 ether; potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 48h;

DOI:10.3390/molecules18021502

Reference yield:

1-dodecylbromide (143-15-7) → [3-dodecyloxy-5-(2-{2-[2-(2-{methyl-[4-(4-nitrophenylazo)phenyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)phenyl]methanol (1447828-68-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; 18-crown-6 ether / acetone / 48 h / Reflux

2: potassium carbonate; 18-crown-6 ether / N,N-dimethyl-formamide / 48 h / 80 °C

With 18-crown-6 ether; potassium carbonate; In N,N-dimethyl-formamide; acetone;

DOI:10.3390/molecules18021502

Reference yield:

(E)-2-(4-((4-nitrophenyl)diazenyl)phenyl)-5,8,11-trioxa-2-azatridecan-13-ol (944550-05-4) → [3-dodecyloxy-5-(2-{2-[2-(2-{methyl-[4-(4-nitrophenylazo)phenyl]amino}ethoxy)ethoxy]ethoxy}ethoxy)phenyl]methanol (1447828-68-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1H-imidazole; triphenylphosphine; iodine / dichloromethane / 6 h / 20 °C

2: potassium carbonate; 18-crown-6 ether / N,N-dimethyl-formamide / 48 h / 80 °C

With 1H-imidazole; 18-crown-6 ether; iodine; potassium carbonate; triphenylphosphine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.3390/molecules18021502

upstream raw materials:

1-dodecylbromide

(E)-2-(4-((4-nitrophenyl)diazenyl)phenyl)-5,8,11-trioxa-2-azatridecan-13-ol

3-dodecyloxy-5-hydroxybenzyl alcohol

5-(hydroxymethyl)benzene-1,3-diol