(R)-4-(4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-hydroxybutyl)benzoic acid

Base Information

Chemical Name:(R)-4-(4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-hydroxybutyl)benzoic acid
CAS No.:1050378-48-7
Molecular Formula:C₁₅H₁₈N₄O₄
Molecular Weight:318.332
Hs Code.:

Synonyms:(R)-4-(4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-hydroxybutyl)benzoic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-4-(4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-hydroxybutyl)benzoic acid

Chemical Property:

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Technology Process of (R)-4-(4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-hydroxybutyl)benzoic acid

There total 1 articles about (R)-4-(4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-hydroxybutyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1050378-45-4
methyl (R)-4-(4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-hydroxybutyl)benzoate

: 1050378-48-7
(R)-4-(4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-hydroxybutyl)benzoic acid

Guidance literature:: With lithium hydroxide monohydrate; water; In methanol; at 20 ℃; for 24h;
DOI:10.1021/jm800555h

Reference yield:

: 1050378-48-7
(R)-4-(4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-hydroxybutyl)benzoic acid

: 23150-65-4
L-glutamic dimethyl ester hydrochloride

: 1050373-47-1
dimethyl (S)-2-(4-((R)-4-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-1-hydroxybutyl)benzamido)pentanedioate

Guidance literature:: With sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1021/jm800555h