1,4-bis-(4-(4-(2-(dimethylamino)ethylaminocarbonyl)oxazol-2-yl)phenyl)-1,2,3-triazole

Base Information

Chemical Name:1,4-bis-(4-(4-(2-(dimethylamino)ethylaminocarbonyl)oxazol-2-yl)phenyl)-1,2,3-triazole
CAS No.:1353130-73-0
Molecular Formula:C₃₀H₃₃N₉O₄
Molecular Weight:583.65
Hs Code.:

Synonyms:1,4-bis-(4-(4-(2-(dimethylamino)ethylaminocarbonyl)oxazol-2-yl)phenyl)-1,2,3-triazole

Suppliers and Price of 1,4-bis-(4-(4-(2-(dimethylamino)ethylaminocarbonyl)oxazol-2-yl)phenyl)-1,2,3-triazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,4-bis-(4-(4-(2-(dimethylamino)ethylaminocarbonyl)oxazol-2-yl)phenyl)-1,2,3-triazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,4-bis-(4-(4-(2-(dimethylamino)ethylaminocarbonyl)oxazol-2-yl)phenyl)-1,2,3-triazole

There total 11 articles about 1,4-bis-(4-(4-(2-(dimethylamino)ethylaminocarbonyl)oxazol-2-yl)phenyl)-1,2,3-triazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1353130-40-1
N-(2-(dimethylamino)ethyl)-2-(4-ethynylphenyl)oxazole-4-carboxamide

: 1353130-57-0
N-(2-(dimethylamino)ethyl)-2-(4-azidophenyl)oxazole-4-carboxamide

: 1353130-73-0
1,4-bis-(4-(4-(2-(dimethylamino)ethylaminocarbonyl)oxazol-2-yl)phenyl)-1,2,3-triazole

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; tert-butyl alcohol; at 100 ℃; for 0.416667h; Microwave irradiation;
DOI:10.1016/j.tet.2011.10.066

Reference yield:

: 863640-43-1
4-(trimethylsilanylethynyl)benzamide

: 1353130-73-0
1,4-bis-(4-(4-(2-(dimethylamino)ethylaminocarbonyl)oxazol-2-yl)phenyl)-1,2,3-triazole

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydrogencarbonate / tetrahydrofuran / Reflux; Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: lithium hydroxide / tetrahydrofuran; water / 2 h / 50 °C

2.2: pH 2

3.1: oxalyl dichloride / tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

4.1: dichloromethane / 0 - 20 °C / Inert atmosphere

5.1: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol / 0.42 h / 100 °C / Microwave irradiation

With copper(ll) sulfate pentahydrate; oxalyl dichloride; sodium hydrogencarbonate; sodium L-ascorbate; lithium hydroxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol; 1.1: Blümlein-Lewy oxazole synthesis;
DOI:10.1016/j.tet.2011.10.066

Reference yield:

: 1353130-37-6
C₁₂H₇NO₃

: 1353130-73-0
1,4-bis-(4-(4-(2-(dimethylamino)ethylaminocarbonyl)oxazol-2-yl)phenyl)-1,2,3-triazole

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl dichloride / tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

2: dichloromethane / 0 - 20 °C / Inert atmosphere

3: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol / 0.42 h / 100 °C / Microwave irradiation

With copper(ll) sulfate pentahydrate; oxalyl dichloride; sodium L-ascorbate; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1016/j.tet.2011.10.066