3-benzyloxy-1,2,5,6-tetramethoxyphenanthrene

Base Information

Chemical Name:3-benzyloxy-1,2,5,6-tetramethoxyphenanthrene
CAS No.:909767-02-8
Molecular Formula:C₂₅H₂₄O₅
Molecular Weight:404.463
Hs Code.:

Synonyms:3-benzyloxy-1,2,5,6-tetramethoxyphenanthrene

Suppliers and Price of 3-benzyloxy-1,2,5,6-tetramethoxyphenanthrene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-benzyloxy-1,2,5,6-tetramethoxyphenanthrene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-benzyloxy-1,2,5,6-tetramethoxyphenanthrene

There total 6 articles about 3-benzyloxy-1,2,5,6-tetramethoxyphenanthrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 909767-01-7
5-benzyloxy-3,4,2',3'-tetramethoxybiphenyl-2,6'-divinylbiphenyl

: 909767-02-8
3-benzyloxy-1,2,5,6-tetramethoxyphenanthrene

Guidance literature:: With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 40 ℃; for 2h;
DOI:10.1021/ol0613564

Reference yield:

: 6-amino-4-benzyloxy-2,3-dimethoxy-benzaldehyde

: 909767-02-8
3-benzyloxy-1,2,5,6-tetramethoxyphenanthrene

Guidance literature:: Multi-step reaction with 4 steps

1.1: t-BuONO; aq. HBF₄ / acetonitrile / 1 h / 0 °C

1.2: 1.18 g / aq. KI / acetonitrile / 16 h / 0 - 20 °C

2.1: 79 percent / Pd(dppf)Cl₂*CH₂Cl₂; K₂CO₃ / dimethylsulfoxide / 16 h / 80 °C

3.1: 93 percent / n-BuLi / tetrahydrofuran; hexane / -78 - 20 °C

4.1: 99 percent / Grubbs second generation ruthenium catalyst / CH₂Cl₂ / 2 h / 40 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; tetrafluoroboric acid; n-butyllithium; tert.-butylnitrite; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate; In tetrahydrofuran; hexane; dichloromethane; dimethyl sulfoxide; acetonitrile; 2.1: Suzuki cross-coupling / 3.1: Wittig reaction;
DOI:10.1021/ol0613564

Reference yield:

: 909766-97-8
4-benzyloxy-2,3-dimethoxy-6-nitrobenzaldehyde

: 909767-02-8
3-benzyloxy-1,2,5,6-tetramethoxyphenanthrene

Guidance literature:: Multi-step reaction with 5 steps

1.1: FeSO₄*7H₂O; aq. NH₄OH / methanol / 0.17 h / 80 °C

2.1: t-BuONO; aq. HBF₄ / acetonitrile / 1 h / 0 °C

2.2: 1.18 g / aq. KI / acetonitrile / 16 h / 0 - 20 °C

3.1: 79 percent / Pd(dppf)Cl₂*CH₂Cl₂; K₂CO₃ / dimethylsulfoxide / 16 h / 80 °C

4.1: 93 percent / n-BuLi / tetrahydrofuran; hexane / -78 - 20 °C

5.1: 99 percent / Grubbs second generation ruthenium catalyst / CH₂Cl₂ / 2 h / 40 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; ammonium hydroxide; tetrafluoroboric acid; n-butyllithium; tert.-butylnitrite; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; potassium carbonate; iron(II) sulfate; In tetrahydrofuran; methanol; hexane; dichloromethane; dimethyl sulfoxide; acetonitrile; 3.1: Suzuki cross-coupling / 4.1: Wittig reaction;
DOI:10.1021/ol0613564