Technology Process of C23H27BrN6O4S
There total 10 articles about C23H27BrN6O4S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
triethylamine;
In
methanol;
at 70 ℃;
for 3h;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: caesium carbonate / N,N-dimethyl-formamide / 4 h
2.1: sodium bis(trimethylsilyl)amide / tetrahydrofuran; hexanes / -78 - -40 °C
2.2: -78 - -40 °C
2.3: -78 - 20 °C
3.1: hydrazinium monoacetate / ethanol / 16 h / 20 °C
4.1: caesium carbonate / N,N-dimethyl-formamide / 48 h / 110 °C
5.1: trichlorophosphate / 1 h / 110 °C
5.2: 0.5 h / 0 °C
6.1: HATU / N,N-dimethyl-formamide / 1 h / 20 °C
6.2: 17 h / 20 °C
7.1: triethylamine / methanol / 3 h / 70 °C
With
sodium bis(trimethylsilyl)amide; hydrazinium monoacetate; caesium carbonate; triethylamine; HATU; trichlorophosphate;
In
tetrahydrofuran; methanol; hexanes; ethanol; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium bis(trimethylsilyl)amide / tetrahydrofuran / 0.42 h / -78 - -20 °C / Inert atmosphere
1.2: 3.08 h / -78 - -45 °C
1.3: -78 - 20 °C
2.1: hydrazinium monoacetate / ethanol / 16 h / 20 °C
3.1: caesium carbonate / N,N-dimethyl-formamide / 48 h / 110 °C
4.1: trichlorophosphate / 1 h / 110 °C
4.2: 0.5 h / 0 °C
5.1: HATU / N,N-dimethyl-formamide / 1 h / 20 °C
5.2: 17 h / 20 °C
6.1: triethylamine / methanol / 3 h / 70 °C
With
sodium bis(trimethylsilyl)amide; hydrazinium monoacetate; caesium carbonate; triethylamine; HATU; trichlorophosphate;
In
tetrahydrofuran; methanol; ethanol; N,N-dimethyl-formamide;
