NSC 247030

Base Information

• Chemical Name: NSC 247030
• CAS No.: 114727-43-4
• Molecular Formula: C₁₅H₉Cl₂NO
• Molecular Weight: 290.149
• Mol file: 114727-43-4.mol

Synonyms:SU₅₂₀₁

Chemical Property of NSC 247030

Chemical Property:

• Melting Point: 195-197 °C
• Boiling Point: 505.7±50.0 °C(Predicted)
• PKA: 12.54±0.20(Predicted)
• Density: 1.431±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

NSC247030 >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of NSC 247030

There total 2 articles about NSC 247030 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2-oxoindole (59-48-3) + 3,4-dichlorobenzaldehyde (6287-38-3) → SU5201 (114727-43-4)

Guidance literature:

With [1-(3-sulfonic acid)]propyl-3-methylimidazolium hydrogen sulfate; at 80 ℃; for 1.66667h;

DOI:10.1515/HC.2008.14.4.263

Reference yield:

→ SU5201 (114727-43-4)

Guidance literature:

Reference yield:

SU5201 (114727-43-4) → 3-(3,4-dichlorobenzyl)oxindole-1-acetic acid

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, 25 deg C, 15 min, 2.) DMF, 30 min

2: 73 percent / H₂, AcOH / 5percent Pd/C / ethyl acetate / 3 h

With hydrogen; sodium hydride; acetic acid; palladium on activated charcoal; In ethyl acetate;

DOI:10.1016/0223-5234(92)90112-E

upstream raw materials:

2-oxoindole

3,4-dichlorobenzaldehyde

Downstream raw materials:

2-{3-[1-(3,4-Dichloro-phenyl)-meth-(E)-ylidene]-2-oxo-2,3-dihydro-indol-1-yl}-propionic acid benzyl ester

cis-3-(3,4-dichlorobenzylidene)oxindole-1-acetic acid benzyl ester