4-Nitro-benzoic acid (1S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester

Base Information

Chemical Name:4-Nitro-benzoic acid (1S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester
CAS No.:597542-17-1
Molecular Formula:C₁₈H₂₅NO₅Si
Molecular Weight:363.486
Hs Code.:

Synonyms:4-Nitro-benzoic acid (1S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester

Suppliers and Price of 4-Nitro-benzoic acid (1S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-Nitro-benzoic acid (1S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Nitro-benzoic acid (1S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester

There total 4 articles about 4-Nitro-benzoic acid (1S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 120520-91-4
(1R,4S)-4-(tert-butyldimethylsilyloxy)cyclopent-2-enol

: 62-23-7
4-nitro-benzoic acid

: 597542-17-1
4-Nitro-benzoic acid (1S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran;
DOI:10.1016/S0960-894X(02)00654-6

Reference yield:

: 60410-16-4
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

: 597542-17-1
4-Nitro-benzoic acid (1S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / imidazole / tetrahydrofuran / 24 h / 20 °C

2: 90 percent / NaOMe; MeOH / 24 h / 20 °C

3: 81 percent / triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 18 h / 20 - 40 °C

With 1H-imidazole; methanol; sodium methylate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 3: Mitsunobu reaction;
DOI:10.1021/jm0205604

Reference yield:

: 115074-49-2
(1R,4S)-4-[(tert-butyldimethylsilyl)oxy]-2-cyclopentene-1-yl acetate

: 597542-17-1
4-Nitro-benzoic acid (1S,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / NaOMe; MeOH / 24 h / 20 °C

2: 81 percent / triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 18 h / 20 - 40 °C

With methanol; sodium methylate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; 2: Mitsunobu reaction;
DOI:10.1021/jm0205604