N-[4-[(Methylsulfonyl)amino]phenyl]-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide

Base Information

Chemical Name:N-[4-[(Methylsulfonyl)amino]phenyl]-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide
CAS No.:135036-42-9
Molecular Formula:C₂₅H₂₈N₄O₃S
Molecular Weight:464.588
Hs Code.:

Synonyms:N-[4-[(Methylsulfonyl)amino]phenyl]-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide

Suppliers and Price of N-[4-[(Methylsulfonyl)amino]phenyl]-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[4-[(Methylsulfonyl)amino]phenyl]-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[4-[(Methylsulfonyl)amino]phenyl]-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide

There total 5 articles about N-[4-[(Methylsulfonyl)amino]phenyl]-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: tin(II)chloride dihydrate

: aq. sodium bicarbonate

: aq. sodium chloride

: 135063-15-9
N-(4-nitrophenyl)-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide

: 135036-42-9
N-[4-[(Methylsulfonyl)amino]phenyl]-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide

Guidance literature:: In water; ethyl acetate; acetonitrile;

Reference yield:

: 7766-38-3
N-(4-nitrophenyl) acrylamide

: 135036-42-9
N-[4-[(Methylsulfonyl)amino]phenyl]-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / bromine / CCl₄ / 96 h / Ambient temperature

2: 34 percent / triethylamine / dimethylformamide / 48 h / 105 °C

3: tin chloride dihydrate / ethyl acetate / 1 h / Heating

4: acetonitrile / 0.33 h / 60 °C

With tin chloride dihydrate; bromine; triethylamine; In tetrachloromethane; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00082a016

Reference yield:

: 135036-38-3
2,3-dibromo-N-(4-nitrophenyl)propanamide

: 135036-42-9
N-[4-[(Methylsulfonyl)amino]phenyl]-1-phenyl-4-(phenylmethyl)-2-piperazinecarboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: 34 percent / triethylamine / dimethylformamide / 48 h / 105 °C

2: tin chloride dihydrate / ethyl acetate / 1 h / Heating

3: acetonitrile / 0.33 h / 60 °C

With tin chloride dihydrate; triethylamine; In ethyl acetate; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/jm00082a016