3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α,β-D-xylopyranosyl trichloroacetimidate

Base Information

• Chemical Name: 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α,β-D-xylopyranosyl trichloroacetimidate
• CAS No.: 1407493-85-9
• Molecular Formula: C₂₁H₂₆Cl₃NO₉
• Molecular Weight: 542.798
• Mol file: 1407493-85-9.mol

Synonyms:3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α,β-D-xylopyranosyl trichloroacetimidate

Chemical Property of 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α,β-D-xylopyranosyl trichloroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α,β-D-xylopyranosyl trichloroacetimidate

There total 5 articles about 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α,β-D-xylopyranosyl trichloroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α,β-D-xylopyranoside + trichloroacetonitrile (545-06-2) → 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α,β-D-xylopyranosyl trichloroacetimidate (1407493-85-9)

Guidance literature:

With potassium carbonate; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tet.2015.05.058

Reference yield:

allyl 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α-D-xylopyranoside → 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α,β-D-xylopyranosyl trichloroacetimidate (1407493-85-9)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium dichloride / methanol / 3 h / 20 °C

2: potassium carbonate / dichloromethane / 20 °C

With potassium carbonate; palladium dichloride; In methanol; dichloromethane;

DOI:10.1016/j.tet.2015.05.058

Reference yield:

allyl α-D-xylopyranoside (140420-69-5) → 3,4-O-(2',3'-dimethoxybutane-2',3'-diyl)-2-O-(4-methoxybenzoyl)-α,β-D-xylopyranosyl trichloroacetimidate (1407493-85-9)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine / -40 - 20 °C

2: camphor-10-sulfonic acid / methanol / 16 h / Reflux

3: palladium dichloride / methanol / 3 h / 20 °C

4: potassium carbonate / dichloromethane / 20 °C

With pyridine; camphor-10-sulfonic acid; potassium carbonate; palladium dichloride; In methanol; dichloromethane;

DOI:10.1016/j.tet.2015.05.058

upstream raw materials:

trichloroacetonitrile

allyl α-D-xylopyranoside

4-methoxy-benzoyl chloride

Refernces