n-Hydroxy-n'-phenylbenzenecarboximidamide

Base Information

• Chemical Name: n-Hydroxy-n'-phenylbenzenecarboximidamide
• CAS No.: 3488-57-1
• Molecular Formula: C13H12N2O
• Molecular Weight: 212.251
• European Community (EC) Number: 683-760-1
• NSC Number: 140038
• DSSTox Substance ID: DTXSID50956361
• Nikkaji Number: J2.555.241E
• Mol file: 3488-57-1.mol

Synonyms:n-hydroxy-n'-phenylbenzenecarboximidamide;3488-57-1;N'-Hydroxy-N-phenylbenzenecarboximidamide;(E)-N'-hydroxy-N-phenylbenzenecarboximidamide;benzanilidoxime;Benzanilidoxim;NSC140038;N-Phenyl-benzamide oxime;SCHEMBL7637584;N-Hydroxy-N'-phenylbenzimidamide;DTXSID50956361;LQZPIDPVRIFWFJ-UHFFFAOYSA-N;(E)-N'-Hydroxy-N-phenylbenzimidamide;(Z)-N'-Hydroxy-N-phenylbenzimidamide;(Z)-N-Hydroxy-N'-phenylbenzimidamide;AKOS005094138;AKOS024332008;NSC-140038;N'-Hydroxy-N-phenylbenzenecarboximidamide #;5P-051;1807774-60-2;2365421-53-8;53442-06-1

Chemical Property of n-Hydroxy-n'-phenylbenzenecarboximidamide

Chemical Property:

• Boiling Point: 374.6°Cat760mmHg
• Flash Point: 180.4°C
• Density: 1.1g/cm³
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 212.094963011
• Heavy Atom Count: 16
• Complexity: 228

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=NC2=CC=CC=C2)NO

Technology Process of n-Hydroxy-n'-phenylbenzenecarboximidamide

There total 15 articles about n-Hydroxy-n'-phenylbenzenecarboximidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-phenyl benzoyl amide (93-98-1,5705-51-1) → (Z)-N'-hydroxy-N-phenylbenzimidamide (3488-57-1)

Guidance literature:

With hydroxylamine hydrochloride; triethylamine; triphenylphosphine; In dichloromethane; at 0 - 25 ℃; for 2h; Reagent/catalyst;

DOI:10.1039/c8ra08207c

Reference yield: 42.0%

aniline (62-53-3) + benzohydroximoyl chloride (698-16-8) → N-phenylbenzamidoxime (3488-57-1)

Guidance literature:

In N,N-dimethyl-formamide; at 0 - 20 ℃;

DOI:10.1016/j.tet.2016.03.070

Reference yield:

Benzaldoxime (932-90-1) → N-phenylbenzamidoxime (3488-57-1)

Guidance literature:

Multi-step reaction with 2 steps

1: N-chloro-succinimide / N,N-dimethyl-formamide / 2 h / 70 °C

2: N,N-dimethyl-formamide / 12 h / 0 - 20 °C

With N-chloro-succinimide; In N,N-dimethyl-formamide;

DOI:10.1021/ol403645y

upstream raw materials:

benzonitrile oxide

aniline

N-phenyl-benzimidoyl chloride

benzohydroximoyl chloride

Downstream raw materials:

3,4-diphenyl-1,2,4-oxadiazol-5(4H)-one

6-nitro-2-phenylbenzo[d]oxazole

N-phenylbenzamidine

N-benzyloxy-N'-phenyl-benzamidine