4-nitrophenyl 5-acetamido-3,4,5-trideoxy-4-(1-triazolyl)-α-D-glycero-D-galacto-non-2-ulpyranosylonic acid

Base Information

Chemical Name:4-nitrophenyl 5-acetamido-3,4,5-trideoxy-4-(1-triazolyl)-α-D-glycero-D-galacto-non-2-ulpyranosylonic acid
CAS No.:1453411-69-2
Molecular Formula:C₁₉H₂₃N₅O₁₀
Molecular Weight:481.419
Hs Code.:

Synonyms:4-nitrophenyl 5-acetamido-3,4,5-trideoxy-4-(1-triazolyl)-α-D-glycero-D-galacto-non-2-ulpyranosylonic acid

Suppliers and Price of 4-nitrophenyl 5-acetamido-3,4,5-trideoxy-4-(1-triazolyl)-α-D-glycero-D-galacto-non-2-ulpyranosylonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-nitrophenyl 5-acetamido-3,4,5-trideoxy-4-(1-triazolyl)-α-D-glycero-D-galacto-non-2-ulpyranosylonic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-nitrophenyl 5-acetamido-3,4,5-trideoxy-4-(1-triazolyl)-α-D-glycero-D-galacto-non-2-ulpyranosylonic acid

There total 7 articles about 4-nitrophenyl 5-acetamido-3,4,5-trideoxy-4-(1-triazolyl)-α-D-glycero-D-galacto-non-2-ulpyranosylonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 1453411-80-7
methyl (4-nitrophenyl 5-acetamido-4-(1-triazolyl)-3,4,5-trideoxy-D-glycero-α-D-galacto-non-2-ulopyranosid)onate

: 1453411-69-2
4-nitrophenyl 5-acetamido-3,4,5-trideoxy-4-(1-triazolyl)-α-D-glycero-D-galacto-non-2-ulpyranosylonic acid

Guidance literature:: methyl (4-nitrophenyl 5-acetamido-4-(1-triazolyl)-3,4,5-trideoxy-D-glycero-α-D-galacto-non-2-ulopyranosid)onate; With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 0 ℃; for 0.5h;

In tetrahydrofuran; water;
DOI:10.1021/ja405916q

Reference yield:

: 108740-39-2,6931-68-6,72690-21-2,73208-82-9,108740-37-0,108740-38-1,119241-63-3,119241-64-4,119241-65-5,147129-72-4,147129-73-5,74006-95-4
(1S,2R)-1-((2R,3R,4S,6R)-3-acetamido-4,6-diacetoxy-6-(methoxycarbonyl)tetrahydro-2H-pyran-2-yl)propane-1,2,3-triyl triacetate

: 1453411-69-2
4-nitrophenyl 5-acetamido-3,4,5-trideoxy-4-(1-triazolyl)-α-D-glycero-D-galacto-non-2-ulpyranosylonic acid

Guidance literature:: Multi-step reaction with 7 steps

1.1: trimethylsilyl trifluoromethanesulfonate / ethyl acetate / 3 h / 50 °C / Inert atmosphere

2.1: trimethylsilylazide / tert-butyl alcohol / 12 h / 80 °C / Inert atmosphere

3.1: lithium chloride / 2 h / 0.2 Torr / Molecular sieve

4.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 h / 0 - 20 °C

5.1: toluene / 3 h / 65 °C / Inert atmosphere

6.1: sodium methylate / methanol / 0.5 h / 0 °C

6.2: Amberlite IR-120 resin (NH₄⁺ form)

7.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 0.5 h / 0 °C

7.2: Amberlite IR-120 resin (NH₄⁺ form)

With lithium hydroxide monohydrate; trimethylsilyl trifluoromethanesulfonate; trimethylsilylazide; sodium methylate; N-ethyl-N,N-diisopropylamine; lithium chloride; In tetrahydrofuran; methanol; water; ethyl acetate; toluene; acetonitrile; tert-butyl alcohol;
DOI:10.1021/ja405916q

Reference yield:

: 163860-77-3
methyl (5-acetamido-7,8,9-tri-O-acetyl-4-azido-3,4,5-trideoxy-D-glycero-β-D-galacto-non-2-ulopyranosyl)onate chloride

: 1453411-69-2
4-nitrophenyl 5-acetamido-3,4,5-trideoxy-4-(1-triazolyl)-α-D-glycero-D-galacto-non-2-ulpyranosylonic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: N-ethyl-N,N-diisopropylamine / acetonitrile / 20 h / 0 - 20 °C

2.1: toluene / 3 h / 65 °C / Inert atmosphere

3.1: sodium methylate / methanol / 0.5 h / 0 °C

3.2: Amberlite IR-120 resin (NH₄⁺ form)

4.1: lithium hydroxide monohydrate / tetrahydrofuran; water / 0.5 h / 0 °C

4.2: Amberlite IR-120 resin (NH₄⁺ form)

With lithium hydroxide monohydrate; sodium methylate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; methanol; water; toluene; acetonitrile;
DOI:10.1021/ja405916q