Celgosivir hydrochloride

Base Information

Chemical Name:Celgosivir hydrochloride
CAS No.:141117-12-6
Molecular Formula:C₁₂H₂₁NO₅*ClH
Molecular Weight:295.763
Hs Code.:
UNII:70U2NQU0FP
DSSTox Substance ID:DTXSID50161574
Wikidata:Q27265897
NCI Thesaurus Code:C87464
ChEMBL ID:CHEMBL2105801
Mol file:141117-12-6.mol

Synonyms:(1S,6S,7S,8R,8aR)-octahydro-1,7,8-trihydroxy-6-indolizinyl butyrate;(1S,6S,7S,8R,8aR)-octahydro-1,7,8-trihydroxy-6-indolizinyl butyrate, hydrochloride;6-O-butanoylcastanospermine;BuCast;butanoic acid, octahydro-1,7,8-trihydroxy-6-indolizinyl ester, (1S-(1alpha,6beta,7alpha,8beta,8abeta))-;celgosivir;celgosivir HCl;celgosivir hydrochloride;MBI 3253;MBI-3253;MBI3253;MDL 28,574;MDL 28,574A;MDL 28574;MDL-28,574A;MDL-28574;MX 3253;MX-3253;MX3253

Suppliers and Price of Celgosivir hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

CSNpharm
CelgosivirHCl
1mg
$ 153.00

CSNpharm
CelgosivirHCl
50mg
$ 1836.00

ChemScene
Celgosivirhydrochloride >98.0%
25mg
$ 1200.00

ChemScene
Celgosivirhydrochloride >98.0%
10mg
$ 600.00

ChemScene
Celgosivirhydrochloride >98.0%
5mg
$ 420.00

ChemScene
Celgosivirhydrochloride >98.0%
1mg
$ 180.00

ChemScene
Celgosivirhydrochloride >98.0%
50mg
$ 2160.00

American Custom Chemicals Corporation
CELGOSIVIR HYDROCHLORIDE 95.00%
100MG
$ 2625.00

Total 7 raw suppliers

Chemical Property of Celgosivir hydrochloride

Chemical Property:

Vapor Pressure:6.34E-09mmHg at 25°C
Boiling Point:422.9°C at 760 mmHg
Flash Point:209.6°C
PSA：90.23000
LogP:-0.39120
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:295.1186505
Heavy Atom Count:19
Complexity:311

Purity/Quality:

98% ^*data from raw suppliers

CelgosivirHCl ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC(=O)OC1CN2CCC(C2C(C1O)O)O.Cl
Isomeric SMILES:CCCC(=O)O[C@H]1CN2CC[C@@H]([C@@H]2[C@H]([C@@H]1O)O)O.Cl
Recent ClinicalTrials:A Study of the Safety and Efficacy of Chronically Administered MDL 28,574A in the Treatment of HIV-Infected Patients

Technology Process of Celgosivir hydrochloride

There total 1 articles about Celgosivir hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.4%

: 79831-76-8
(1S,6S,7R,8R,8aR)-2,6,7,8-tetrahydroxy-indolizidine

: 141-75-3
butyryl chloride

: 141117-12-6
Celgosivir hydrochloride

Guidance literature:: (1S,6S,7R,8R,8aR)-2,6,7,8-tetrahydroxy-indolizidine; With bis(tri-n-butyltin)oxide; In toluene; for 3.33h; Heating / reflux;

butyryl chloride; In toluene; at -13 - -8 ℃; for 0.166667h;

With hydrogenchloride; In ethanol; isopropyl alcohol; toluene; at 18 - 30 ℃;