1,11-Dioxa[11]paracyclophane

Base Information

• Chemical Name: 1,11-Dioxa[11]paracyclophane
• CAS No.: 6571-51-3
• Molecular Formula: C₁₅H₂₂O₂
• Molecular Weight: 234.338
• Mol file: 6571-51-3.mol

Synonyms:Dioxa<11>paracyclophane

Chemical Property of 1,11-Dioxa[11]paracyclophane

Chemical Property:

• Melting Point: 53.0 to 57.0 °C
• Solubility.: soluble in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,11-Dioxa[11]paracyclophane >97.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,11-Dioxa[11]paracyclophane

There total 5 articles about 1,11-Dioxa[11]paracyclophane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

p-hydroxyphenyl 9-bromononyl ether (132568-33-3) → Dioxa<11>paracyclophane (6571-51-3)

Guidance literature:

With tetramethyl ammoniumhydroxide; In water; dimethyl sulfoxide; at 80 ℃; for 6h; Inert atmosphere;

DOI:10.1021/ol100444u

Reference yield: 31.0%

1,9-Dibromononane (4549-33-1) + hydroquinone (123-31-9,8027-02-9) → Dioxa<11>paracyclophane (6571-51-3)

Guidance literature:

With potassium carbonate; In i-Amyl alcohol;

Reference yield:

1,9-Dibromononane (4549-33-1) → Dioxa<11>paracyclophane (6571-51-3)

Guidance literature:

Multi-step reaction with 2 steps

1: methanol. KOH; ethanol

2: isoamyl alcohol; potassium carbonate

With potassium hydroxide; ethanol; i-Amyl alcohol; potassium carbonate;

upstream raw materials:

p-hydroxyphenyl 9-bromononyl ether

1,9-Dibromononane

hydroquinone

Downstream raw materials:

(rp)-1,11-dioxa-[11]paracyclophane-13-carboxylic acid

Refernces

• 1、 Hochmuth, Detlev H.,Koenig, Wilfried A.. "Determination of the rotational energy barrier of planar-chiral cyclophanes using dynamic enantioselective gas chromatography and computer simulation". . p. 947 - 951. Retrieved 2007/10/03.