(E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol

Base Information

Chemical Name:(E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol
CAS No.:122821-99-2
Molecular Formula:C₅₃H₆₆O₆Si₂
Molecular Weight:855.274
Hs Code.:

(E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis<O-(tert-butyldiphenylsilyl)>-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol

Synonyms:(E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol

Suppliers and Price of (E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol

There total 16 articles about (E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 122821-98-1
Methyl (E)-5,9:8,12-dianhydro-10-O-benzyl-6,13-bis-2,3,4,7,11-pentadeoxy-9-C-methyl-D-threo-L-allo-tridec-2-enoate

: 122821-99-2
(E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; at -78 ℃; for 0.5h;
DOI:10.1021/ja00199a031

Reference yield:

: 122821-89-0
[(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-hydroxy-3-methyl-tetrahydro-pyran-2-yl]-acetaldehyde

: 122821-99-2
(E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol

Guidance literature:: Multi-step reaction with 8 steps

1: tetrahydrofuran / 0.5 h / 0 °C

2: 88 percent / imidazole / dimethylformamide / 16 h / Ambient temperature

3: 1.) ozone, 2.) dimethylsulfide, triphenylphosphine / 1.) CH₂Cl₂, -78 deg C, 2 h, 2.) 3 h

4: benzene / 6 h / 25 °C

5: 92 percent / NaH / tetrahydrofuran / 5 h / 25 °C

6: DIBAL / CH₂Cl₂ / 0.25 h / -78 °C

7: benzene / 6 h / 25 °C

8: 88 percent / DIBAL / CH₂Cl₂ / 0.5 h / -78 °C

With 1H-imidazole; dimethylsulfide; sodium hydride; diisobutylaluminium hydride; ozone; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/ja00199a031

Reference yield:

: 122821-85-6,122920-04-1
2,6-Anhydro-4-O-benzyl-1-O-(tert-butyldiphenylsilyl)-3,7,8,9-teradeoxy-5-C-methyl-D-altro-non-8-enitol

: 122821-99-2
(E)-2,6:5,9-Dianhydro-4-O-benzyl-1,8-bis-3,7,10,11,12-pentadeoxy-5-C-methyl-D-erythro-L-altro-tridec-11-enitol

Guidance literature:: Multi-step reaction with 9 steps

1: 1.) ozone, 2.) dimethylsulfide, triphenylphosphine / 1.) CH₂Cl₂, -78 deg C, 2 h, 2.) 3 h

2: tetrahydrofuran / 0.5 h / 0 °C

3: 88 percent / imidazole / dimethylformamide / 16 h / Ambient temperature

4: 1.) ozone, 2.) dimethylsulfide, triphenylphosphine / 1.) CH₂Cl₂, -78 deg C, 2 h, 2.) 3 h

5: benzene / 6 h / 25 °C

6: 92 percent / NaH / tetrahydrofuran / 5 h / 25 °C

7: DIBAL / CH₂Cl₂ / 0.25 h / -78 °C

8: benzene / 6 h / 25 °C

9: 88 percent / DIBAL / CH₂Cl₂ / 0.5 h / -78 °C

With 1H-imidazole; dimethylsulfide; sodium hydride; diisobutylaluminium hydride; ozone; triphenylphosphine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/ja00199a031