(3RS)-ethyl 2-(o-nitrobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate

Base Information

Chemical Name:(3RS)-ethyl 2-(o-nitrobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate
CAS No.:108343-83-5
Molecular Formula:C₂₁H₂₁N₃O₄
Molecular Weight:379.415
Hs Code.:

Synonyms:(3RS)-ethyl 2-(o-nitrobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate

Suppliers and Price of (3RS)-ethyl 2-(o-nitrobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of (3RS)-ethyl 2-(o-nitrobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Pictogram(s):
Hazard Codes:

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Technology Process of (3RS)-ethyl 2-(o-nitrobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate

There total 1 articles about (3RS)-ethyl 2-(o-nitrobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 3958-60-9
2-nitrophenylmethyl bromide

: 84518-77-4,41300-23-6
ethyl 1,2,3,4-tetrahydro-β-carboline-3-carboxylate

: 108343-83-5
(3RS)-ethyl 2-(o-nitrobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate

Guidance literature:: With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate; In dichloromethane; for 22h; Ambient temperature;
DOI:10.1021/jm00390a023

Reference yield: 90.0%

: 108343-83-5
(3RS)-ethyl 2-(o-nitrobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate

: 108343-84-6
(3RS)-ethyl 2-(o-aminobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate

Guidance literature:: With hydrogen; nickel; In ethanol; for 4h; under 760 Torr;
DOI:10.1021/jm00390a023

Reference yield:

: 108343-83-5
(3RS)-ethyl 2-(o-nitrobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylate

: 108343-85-7
(3RS)-2-(o-aminobenzyl)-1,3,4,9-tetrahydro-β-carboline-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / H₂ / Raney nickel / ethanol / 4 h / 760 Torr

2: 60 percent / 1N NaOH / ethanol; H₂O / 2 h / Heating

With sodium hydroxide; hydrogen; nickel; In ethanol; water;
DOI:10.1021/jm00390a023