4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid

Base Information

Chemical Name:4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid
CAS No.:5623-18-7
Molecular Formula:C15H14N6O3
Molecular Weight:326.31
Hs Code.:
Mol file:5623-18-7.mol

Synonyms:4-[(2-amino-4-oxo-1H-pteridin-6-yl)methyl-methylamino]benzoic acid;

Suppliers and Price of 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N10-MethylPteroicAcid
500mg
$ 1455.00

TRC
N10-MethylPteroicAcid
250mg
$ 810.00

TRC
N10-MethylPteroicAcid
25mg
$ 105.00

Sigma-Aldrich
Methotrexate impurity D European Pharmacopoeia (EP) Reference Standard
m1000008
$ 190.00

Medical Isotopes, Inc.
N10-MethylPteroicAcid
500 mg
$ 2200.00

Medical Isotopes, Inc.
N10-MethylPteroicAcid
50 mg
$ 650.00

Total 13 raw suppliers

Chemical Property of 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid

Chemical Property:

Vapor Pressure:9.06E-19mmHg at 25°C
Melting Point:>245°C (dec.)
Boiling Point:668.3°C at 760 mmHg
PKA:4.74±0.10(Predicted)
Flash Point:357.9°C
PSA：138.09000
Density:1.58g/cm³
LogP:1.21110
Storage Temp.:Refrigerator
Solubility.:Aqueous Base (Slightly), DMSO (Very Slightly, Heated), Methanol (Very Slightly)

Purity/Quality:

97% ^*data from raw suppliers

N10-MethylPteroicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N10-Methyl Pteroic Acid (Methotrexate EP Impurity D) is a Methotrexate (M260675) impurity D. Methotrexate (M260675) impurity D.

Technology Process of 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid

There total 3 articles about 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 150-13-0,159246-81-8,8014-65-1
4-amino-benzoic acid

: 5623-18-7
10-methyl-pteroic acid

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH solution; aqueous formaldehyde; zinc

With sodium hydroxide; formaldehyd; zinc;
DOI:10.1021/ja01185a081