N,N-diethyl-N-[3-isopropoxy-4-(1-propenyl)-phenyl]amine

Base Information

• Chemical Name: N,N-diethyl-N-[3-isopropoxy-4-(1-propenyl)-phenyl]amine
• CAS No.: 914914-55-9
• Molecular Formula: C₁₆H₂₅NO
• Molecular Weight: 247.381
• Mol file: 914914-55-9.mol

Synonyms:N,N-diethyl-N-[3-isopropoxy-4-(1-propenyl)-phenyl]amine

Chemical Property of N,N-diethyl-N-[3-isopropoxy-4-(1-propenyl)-phenyl]amine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N,N-diethyl-N-[3-isopropoxy-4-(1-propenyl)-phenyl]amine

There total 1 articles about N,N-diethyl-N-[3-isopropoxy-4-(1-propenyl)-phenyl]amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-(diethylamino)-2-isopropoxybenzaldehyde + ethyltriphenylphosphonium bromide (1530-32-1) → N,N-diethyl-N-[3-isopropoxy-4-(1-propenyl)-phenyl]amine (914914-55-9)

Guidance literature:

ethyltriphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 30 ℃; for 3h;

4-(diethylamino)-2-isopropoxybenzaldehyde; In tetrahydrofuran; hexane; at -78 - 20 ℃; Further stages.;

DOI:10.1021/ja063561k

Reference yield: 70.0%

N,N-diethyl-N-[3-isopropoxy-4-(1-propenyl)-phenyl]amine (914914-55-9) + Hoveyda-Grubbs catalyst second generation (301224-40-8) → ((2,4,6-trimethylphenyl)2(C3H4N2))Cl2Ru(CH(C6H3)(OC3H7)(4-NEt2))

Guidance literature:

In toluene; byproducts: (=CHC6H3(NEt2)OCH(CH3)2)2; Ru complex was added to stirred soln. of ligand (3 equiv.) in toluene at80°C under Ar; stirred at 80°C for 60 min under Ar; cooled (room temp.); concd. (vac.); chromd. (silica, cyclohexane/EtOAc/Et3N, 4/1/0.1); solvent removed; washed (cold pentane); dried (vac.);

DOI:10.1021/om0607651

Reference yield: 42.0%

N,N-diethyl-N-[3-isopropoxy-4-(1-propenyl)-phenyl]amine (914914-55-9) + [(oTol)RuCl2(PPh3) (Ind)] → [(oTol)RuCl2(Hov)]

Guidance literature:

In chloroform; for 0.75h; Inert atmosphere; Schlenk technique; Reflux;

upstream raw materials:

ethyltriphenylphosphonium bromide