O-[methyl 4-O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-2-O-levulinoyl-L-idopyranosyluronate] trichloroacetamidate

Base Information

• Chemical Name: O-[methyl 4-O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-2-O-levulinoyl-L-idopyranosyluronate] trichloroacetamidate
• CAS No.: 857895-88-6
• Molecular Formula: C₄₁H₄₃Cl₃N₄O₁₃
• Molecular Weight: 906.17

Synonyms:O-[methyl 4-O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-2-O-levulinoyl-L-idopyranosyluronate] trichloroacetamidate

Chemical Property of O-[methyl 4-O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-2-O-levulinoyl-L-idopyranosyluronate] trichloroacetamidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O-[methyl 4-O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-2-O-levulinoyl-L-idopyranosyluronate] trichloroacetamidate

There total 2 articles about O-[methyl 4-O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-2-O-levulinoyl-L-idopyranosyluronate] trichloroacetamidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

methyl 4-O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-2-O-levulinoyl-L-idopyranosuronate + trichloroacetonitrile (545-06-2) → O-[methyl 4-O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-2-O-levulinoyl-L-idopyranosyluronate] trichloroacetamidate (857895-88-6)

Guidance literature:

With potassium carbonate; In dichloromethane; at 20 ℃; for 6h;

DOI:10.1002/ejoc.200400799

Reference yield:

(2R,3S,4S,5R,6R)-3-((2R,4aR,6R,7R,8R,8aS)-7-Azido-8-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-4-benzyloxy-6-(hexyl-dimethyl-silanyloxy)-5-(4-oxo-pentanoyloxy)-tetrahydro-pyran-2-carboxylic acid methyl ester → O-[methyl 4-O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-2-O-levulinoyl-L-idopyranosyluronate] trichloroacetamidate (857895-88-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / (HF)_n*pyridine / tetrahydrofuran / 24 h / -15 - 0 °C

2: 87 percent / K₂CO₃ / CH₂Cl₂ / 6 h / 20 °C

With (HF)_n*pyridine; potassium carbonate; In tetrahydrofuran; dichloromethane;

DOI:10.1002/ejoc.200400799

upstream raw materials:

trichloroacetonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 857895-88-6 O-[methyl 4-O-(2-azido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-α-D-glucopyranosyl)-3-O-benzyl-2-O-levulinoyl-L-idopyranosyluronate] trichloroacetamidate

Send

Send

Metric Ton KG G Pound L ML

Send

Send