C₃₆H₅₂N₆O₉

Base Information

• Chemical Name: C₃₆H₅₂N₆O₉
• CAS No.: 1353742-65-0
• Molecular Formula: C₃₆H₅₂N₆O₉
• Molecular Weight: 712.844
• Mol file: 1353742-65-0.mol

Synonyms:C₃₆H₅₂N₆O₉

Chemical Property of C₃₆H₅₂N₆O₉

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₆H₅₂N₆O₉

There total 8 articles about C₃₆H₅₂N₆O₉ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

C2HF3O2*C10H18N2O3 (1353742-53-6) + C26H36N4O7 (1353742-63-8) → C36H52N6O9 (1353742-65-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1039/c1ob06575k

Reference yield:

C18H24N2O5 (1353742-48-9) → C36H52N6O9 (1353742-65-0)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium hydroxide / tetrahydrofuran; water / 3 h / 0 °C

1.2: pH 2

2.1: pentafluorophenyl diphenyl-phosphinate; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

3.1: sodium hydroxide / tetrahydrofuran; water / 0 - 20 °C

3.2: pH 2

4.1: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane; N,N-dimethyl-formamide / 20 °C

With pentafluorophenyl diphenyl-phosphinate; N-ethyl-N,N-diisopropylamine; HATU; sodium hydroxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1039/c1ob06575k

Reference yield:

2-benzyloxycarbonylamino-(1R,2S)-cyclobutane-1-carboxylic acid (221158-93-6) → C36H52N6O9 (1353742-65-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / dichloromethane / 1.5 h / 20 °C

2.1: sodium hydroxide / tetrahydrofuran; water / 3 h / 0 °C

2.2: pH 2

3.1: pentafluorophenyl diphenyl-phosphinate; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

4.1: sodium hydroxide / tetrahydrofuran; water / 0 - 20 °C

4.2: pH 2

5.1: N-ethyl-N,N-diisopropylamine; HATU / dichloromethane; N,N-dimethyl-formamide / 20 °C

With pentafluorophenyl diphenyl-phosphinate; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; HATU; sodium hydroxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1039/c1ob06575k

upstream raw materials:

C₁₈H₂₄N₂O₅

C₂HF₃O₂*C₁₀H₁₈N₂O₃

C₂₆H₃₆N₄O₇

C₁₇H₂₂N₂O₅