N₃,2-dimethyl-N₃-((1-(2-(4-methoxyphenyl)ethyl)piperidin-4-yl)methyl)-2H-indazole-3-carboxamide

Base Information

• Chemical Name: N₃,2-dimethyl-N₃-((1-(2-(4-methoxyphenyl)ethyl)piperidin-4-yl)methyl)-2H-indazole-3-carboxamide
• CAS No.: 1029644-04-9
• Molecular Formula: C₂₅H₃₂N₄O₂
• Molecular Weight: 420.555

Synonyms:N₃,2-dimethyl-N₃-((1-(2-(4-methoxyphenyl)ethyl)piperidin-4-yl)methyl)-2H-indazole-3-carboxamide

Chemical Property of N₃,2-dimethyl-N₃-((1-(2-(4-methoxyphenyl)ethyl)piperidin-4-yl)methyl)-2H-indazole-3-carboxamide

Chemical Property:

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Technology Process of N₃,2-dimethyl-N₃-((1-(2-(4-methoxyphenyl)ethyl)piperidin-4-yl)methyl)-2H-indazole-3-carboxamide

There total 1 articles about N₃,2-dimethyl-N₃-((1-(2-(4-methoxyphenyl)ethyl)piperidin-4-yl)methyl)-2H-indazole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(1-(2-(4-methoxyphenyl)ethyl)-4-piperidinyl)-N-methylmethanamine (883545-43-5) + 2-methyl-2H-indazole-3-carbonyl chloride (181071-92-1) → N3,2-dimethyl-N3-((1-(2-(4-methoxyphenyl)ethyl)piperidin-4-yl)methyl)-2H-indazole-3-carboxamide (1029644-04-9)

Guidance literature:

In toluene; at 20 ℃; for 18h;

Reference yield:

N3,2-dimethyl-N3-((1-(2-(4-methoxyphenyl)ethyl)piperidin-4-yl)methyl)-2H-indazole-3-carboxamide (1029644-04-9) → N,2-dimethyl-N-[(1-{2-[4-(methyloxy)phenyl]ethyl}piperidin-4-yl)methyl]-2H-indazole-3-carboxamide hydrochloride (1029643-62-6)

Guidance literature:

With hydrogenchloride; In ethanol; at 20 ℃; for 3h;

upstream raw materials:

1-(1-(2-(4-methoxyphenyl)ethyl)-4-piperidinyl)-N-methylmethanamine

2-methyl-2H-indazole-3-carbonyl chloride

Downstream raw materials:

N,2-dimethyl-N-[(1-{2-[4-(methyloxy)phenyl]ethyl}piperidin-4-yl)methyl]-2H-indazole-3-carboxamide hydrochloride

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