3-[tert-butyl-(3-hydroxy-3,3-diphenyl-propyl)-amino]-1,1-diphenyl-propan-1-ol

Base Information

• Chemical Name: 3-[tert-butyl-(3-hydroxy-3,3-diphenyl-propyl)-amino]-1,1-diphenyl-propan-1-ol
• CAS No.: 260370-09-0
• Molecular Formula: C₃₄H₃₉NO₂
• Molecular Weight: 493.689
• Mol file: 260370-09-0.mol

Synonyms:3-[tert-butyl-(3-hydroxy-3,3-diphenyl-propyl)-amino]-1,1-diphenyl-propan-1-ol

Chemical Property of 3-[tert-butyl-(3-hydroxy-3,3-diphenyl-propyl)-amino]-1,1-diphenyl-propan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[tert-butyl-(3-hydroxy-3,3-diphenyl-propyl)-amino]-1,1-diphenyl-propan-1-ol

There total 1 articles about 3-[tert-butyl-(3-hydroxy-3,3-diphenyl-propyl)-amino]-1,1-diphenyl-propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

bromobenzene (108-86-1,52753-63-6) + 3-[tert-butyl-(2-methoxycarbonyl-ethyl)-amino]-propionic acid methyl ester (260370-11-4) → 3-[tert-butyl-(3-hydroxy-3,3-diphenyl-propyl)-amino]-1,1-diphenyl-propan-1-ol (260370-09-0)

Guidance literature:

bromobenzene; With lithium; In diethyl ether;

3-[tert-butyl-(2-methoxycarbonyl-ethyl)-amino]-propionic acid methyl ester; In diethyl ether; at 0 - 20 ℃;

DOI:10.1139/v00-001

Reference yield: 93.0%

tetrabenzylzirconium(IV) (24356-01-2) + 3-[tert-butyl-(3-hydroxy-3,3-diphenyl-propyl)-amino]-1,1-diphenyl-propan-1-ol (260370-09-0) → Zr(4+)*2C(CH3)3N(CH2CH2C(O)(C6H5)2)2(2-)=Zr[C(CH3)3N(CH2CH2C(O)(C6H5)2)2]2

Guidance literature:

In toluene; stirring for 1 h; volatiles were removed under pressure, recrystn. from a mixt. of toluene and hexane;

DOI:10.1139/v00-001

Reference yield:

tetrabenzylzirconium(IV) (24356-01-2) + 3-[tert-butyl-(3-hydroxy-3,3-diphenyl-propyl)-amino]-1,1-diphenyl-propan-1-ol (260370-09-0) → Zr[tert-BuN(CH2CH2C(O)Ph2)2][CH2Ph]2 (260370-16-9)

Guidance literature:

In toluene; under Ar atm. soln. HOCPh2CH2CH2N(t-Bu)CH2CH2CPh2OH in toluene was added dropwise at -78°C to soln. tetrabenzylzirconium in toluene, mixt. was stirred for 30 min; solvent was removed in vacuo, residue was recrystd. from toluene-hexane; elem. anal.;

DOI:10.1021/om9907324

upstream raw materials:

bromobenzene

3-[tert-butyl-(2-methoxycarbonyl-ethyl)-amino]-propionic acid methyl ester

Downstream raw materials:

Zr[tert-BuN(CH₂CH₂C(O)Ph₂)2][CH₂Ph]2