Technology Process of 4-amino-3-cyclohexyl-3-methylbutanoic acid hydrochloride
There total 3 articles about 4-amino-3-cyclohexyl-3-methylbutanoic acid hydrochloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
platinum(IV) oxide; hydrogen;
In
methanol;
at 20 ℃;
for 48h;
DOI:10.1002/anie.201206916
- Guidance literature:
-
Multi-step reaction with 3 steps
1: resin-supported Pro-D-Pro-Aib-(Trp)2-(Leu)25.4 / water / 20 h / 20 °C
2: sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; sodium chlorite / water; tert-butyl alcohol / 0.08 h / 20 °C
3: hydrogen; platinum(IV) oxide / methanol / 48 h / 20 °C
With
platinum(IV) oxide; sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; hydrogen;
In
methanol; water; tert-butyl alcohol;
1: |Michael Addition;
DOI:10.1002/anie.201206916
- Guidance literature:
-
Multi-step reaction with 3 steps
1: C68H100N13O12Pol / water / 20 h / 20 °C
2: sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; sodium chlorite / water; tert-butyl alcohol / 0.08 h / 20 °C
3: hydrogen; platinum(IV) oxide / methanol / 48 h / 20 °C
With
platinum(IV) oxide; sodium chlorite; sodium dihydrogenphosphate dihydrate; 2-methyl-but-2-ene; C68H100N13O12Pol; hydrogen;
In
methanol; water; tert-butyl alcohol;
1: |Michael Addition;
DOI:10.1002/anie.201206916
