1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzyl)benzimidazolium chloride

Base Information

• Chemical Name: 1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzyl)benzimidazolium chloride
• CAS No.: 1360468-65-0
• Molecular Formula: C₂₃H₃₂N₃*Cl
• Molecular Weight: 385.98
• Mol file: 1360468-65-0.mol

Synonyms:1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzyl)benzimidazolium chloride

Chemical Property of 1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzyl)benzimidazolium chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzyl)benzimidazolium chloride

There total 1 articles about 1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzyl)benzimidazolium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3-(chloromethyl)-1,2,4,5-tetramethylbenzene (7435-83-8) + 1-(1-methyl-2-dimethylaminoethyl)benzimidazole (875872-11-0) → 1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzyl)benzimidazolium chloride (1360468-65-0)

Guidance literature:

In N,N-dimethyl-formamide; at 25 - 60 ℃; for 13h; Inert atmosphere;

DOI:10.1080/00958972.2012.654469

Reference yield:

1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzyl)benzimidazolium chloride (1360468-65-0) + silver(l) oxide (20667-12-3) → chloro-[1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzylbenzimidazol-2-ylidene)]silver(I)

Guidance literature:

In dichloromethane; at 20 ℃; for 24h; Molecular sieve;

DOI:10.1016/j.ica.2016.07.055

Reference yield:

1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzyl)benzimidazolium chloride (1360468-65-0) → bis[1-(1-methyl-2-dimethylaminoethyl)-3-(2,3,5,6-tetramethylbenzyl)benzimidazol-2-ylidene]dichloropalladium(II)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 24 h / 20 °C / Molecular sieve

2: dichloromethane / 24 h / 20 °C / Schlenk technique; Inert atmosphere

In dichloromethane;

DOI:10.1016/j.ica.2016.07.055

upstream raw materials:

3-(chloromethyl)-1,2,4,5-tetramethylbenzene

1-(1-methyl-2-dimethylaminoethyl)benzimidazole