4-iodophenyl 2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl ketone

Base Information

Chemical Name:4-iodophenyl 2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl ketone
CAS No.:193966-46-0
Molecular Formula:C₂₇H₂₄INO₂S
Molecular Weight:553.464
Hs Code.:

Synonyms:4-iodophenyl 2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl ketone

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Chemical Property of 4-iodophenyl 2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl ketone

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Technology Process of 4-iodophenyl 2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl ketone

There total 4 articles about 4-iodophenyl 2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 98437-23-1
benzo[b]thiophene-2-boronic acid

: 193966-46-0
4-iodophenyl 2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl ketone

Guidance literature:: Multi-step reaction with 2 steps

1: 38 percent / Pd(PPh₃)4, 2N aq. Na₂CO₃

2: TiCl₄

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; titanium tetrachloride; sodium carbonate;
DOI:10.1016/S0960-894X(98)00746-X

Reference yield:

: 619-58-9
4-iodobenzoic acid

: 193966-46-0
4-iodophenyl 2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl ketone

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂

2: TiCl₄

With thionyl chloride; titanium tetrachloride;
DOI:10.1016/S0960-894X(98)00746-X

Reference yield:

: 1081-73-8
1-[2-(4-bromophenoxy)ethyl]pyrrolidine

: 193966-46-0
4-iodophenyl 2-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]benzo[b]thiophen-3-yl ketone

Guidance literature:: Multi-step reaction with 2 steps

1: 38 percent / Pd(PPh₃)4, 2N aq. Na₂CO₃

2: TiCl₄

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; titanium tetrachloride; sodium carbonate;
DOI:10.1016/S0960-894X(98)00746-X