Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester

Base Information

Chemical Name:Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester
CAS No.:85925-85-5
Molecular Formula:C₂₄H₄₂O₈Si
Molecular Weight:486.678
Hs Code.:

Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester

Synonyms:Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester

Suppliers and Price of Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester

There total 8 articles about Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 85925-84-4
Acetic acid (6R,7S,8S,9S)-7-acetoxy-9-((R)-1-acetoxymethyl-4-hydroxy-4-methyl-cyclohex-2-enyl)-8-(tert-butyl-dimethyl-silanyloxy)-9-methyl-1,4-dioxa-spiro[4.4]non-6-yl ester

: 85925-85-5
Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester

Guidance literature:: With ammonium hydroxide; In methanol; for 16h; Ambient temperature;
DOI:10.1021/ja00351a057

Reference yield:

: 85925-77-5
(6R,7S,8S,9S)-8-(tert-Butyl-dimethyl-silanyloxy)-9-((R)-4-hydroxy-1-hydroxymethyl-4-methyl-cyclohex-2-enyl)-9-methyl-1,4-dioxa-spiro[4.4]nonane-6,7-diol

: 85925-85-5
Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / pyridine / 16 h / Ambient temperature

2: 70 percent / aq. NH₄OH / methanol / 16 h / Ambient temperature

With ammonium hydroxide; In pyridine; methanol;
DOI:10.1021/ja00351a057

Reference yield:

: C₂₃H₃₄O₆Si

: 85925-85-5
Acetic acid (R)-1-[(6S,7S,8S,9R)-7-(tert-butyl-dimethyl-silanyloxy)-8,9-dihydroxy-6-methyl-1,4-dioxa-spiro[4.4]non-6-yl]-4-hydroxy-4-methyl-cyclohex-2-enylmethyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: 99 percent / 16 h / 120 °C

2: 99 percent / NaOAc / acetic acid; H₂O / 1 h / Ambient temperature

3: 95 percent / diisopropylethylamine / tetrahydrofuran / 96 h / Ambient temperature

4: 1.) LDA, 2.) MsCl, imidazole / 1.) THF, -78 deg C, 1 h, 2.) DMF, room temperature, 16 h

5: 90 percent / tetrahydrofuran / 1 h / -78 °C

6: 75 percent / LiAlH₄ / 1,2-dimethoxy-ethane / 1 h / Heating

7: 95 percent / pyridine / 16 h / Ambient temperature

8: 70 percent / aq. NH₄OH / methanol / 16 h / Ambient temperature

With 1H-imidazole; ammonium hydroxide; lithium aluminium tetrahydride; sodium acetate; methanesulfonyl chloride; N-ethyl-N,N-diisopropylamine; lithium diisopropyl amide; In tetrahydrofuran; pyridine; methanol; 1,2-dimethoxyethane; water; acetic acid;
DOI:10.1021/ja00351a057