1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-5-carboxylic acid phenylmethyl ester

Base Information

Chemical Name:1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-5-carboxylic acid phenylmethyl ester
CAS No.:1308719-38-1
Molecular Formula:C₂₃H₂₃N₃O₃
Molecular Weight:389.454
Hs Code.:

Synonyms:1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-5-carboxylic acid phenylmethyl ester

Suppliers and Price of 1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-5-carboxylic acid phenylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-5-carboxylic acid phenylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-5-carboxylic acid phenylmethyl ester

There total 4 articles about 1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-5-carboxylic acid phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1H-imidazole-4-carboxylic acid phenylmethyl ester lithium salt

: 132991-79-8
4-methylbenzenesulfonic acid [5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl ester

: 1308719-86-9
1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-4-carboxylic acid phenylmethyl ester

: 1308719-38-1
1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-5-carboxylic acid phenylmethyl ester

Guidance literature:: In N,N-dimethyl-formamide; at 50 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2011.03.044

Reference yield:

: 103301-78-6,143317-59-3,57171-00-3
methyl (2S)-1-benzyl-5-pyrrolidone-2-carboxylate

: 1308719-86-9
1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-4-carboxylic acid phenylmethyl ester

: 1308719-38-1
1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-5-carboxylic acid phenylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium borohydride / tetrahydrofuran / 20 °C / Inert atmosphere

1.2: 0 °C / Inert atmosphere

2.1: triethylamine / dichloromethane / 0 - 20 °C

3.1: N,N-dimethyl-formamide / 50 °C / Inert atmosphere

With lithium borohydride; triethylamine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2011.03.044

Reference yield:

: 125629-91-6
(S)-5-(hydroxymethyl)-1-(phenylmethyl)-2-pyrrolidinone

: 1308719-86-9
1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-4-carboxylic acid phenylmethyl ester

: 1308719-38-1
1-[[5-oxo-1-(phenylmethyl)-(2S)-pyrrolidinyl]methyl]-1H-imidazole-5-carboxylic acid phenylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 0 - 20 °C

2: N,N-dimethyl-formamide / 50 °C / Inert atmosphere

With triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2011.03.044