N-methyl<2,4,6-2H3>aniline

Base Information

• Chemical Name: N-methyl<2,4,6-2H3>aniline
• CAS No.: 343864-48-2
• Molecular Formula: C₇H₉N
• Molecular Weight: 110.131
• Mol file: 343864-48-2.mol

Synonyms:N-methyl<2,4,6-2H3>aniline

Chemical Property of N-methyl<2,4,6-2H3>aniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-methyl<2,4,6-2H3>aniline

There total 5 articles about N-methyl<2,4,6-2H3>aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-methylaniline (100-61-8) → N-methyl<2,4,6-2H3>aniline (343864-48-2)

Guidance literature:

With water-d2; acetyl chloride; for 24h; Reflux; Inert atmosphere;

DOI:10.1021/acs.joc.5b01875

Reference yield: 91.0%

N-methylaniline hydrochloride (2739-12-0) → N-methyl<2,4,6-2H3>aniline (343864-48-2)

Guidance literature:

With water-d2; for 120h; Reflux;

DOI:10.1021/acs.orglett.6b00949

Reference yield:

2-(N-methylanilino)-2-phenyloct-3-yn-1-ol → N-methyl<2,4,6-2H3>aniline (343864-48-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (triphenylphosphine)gold(I) chloride; silver hexafluoroantimonate / toluene / 80 °C / Inert atmosphere

2: water-d2; trifluoroacetic acid / 24 h / Reflux

With silver hexafluoroantimonate; (triphenylphosphine)gold(I) chloride; water-d2; trifluoroacetic acid; In toluene;

DOI:10.1002/adsc.201701638

upstream raw materials:

N-methylaniline hydrochloride

aniline

N-methylaniline

Downstream raw materials:

bis(cis-2-buten-2-yl)-N-methyl-N-(2,4,6-trideuteriophenyl)boranamine

bis(3,3-dimethyl-trans-1-buten-1-yl)-N-methyl-N-(2,4,6-trideuteriophenyl)boranamine