C₃₁H₄₆N₂O₅

Base Information

• Chemical Name: C₃₁H₄₆N₂O₅
• CAS No.: 848731-62-4
• Molecular Formula: C₃₁H₄₆N₂O₅
• Molecular Weight: 526.717
• Mol file: 848731-62-4.mol

Synonyms:C₃₁H₄₆N₂O₅

Chemical Property of C₃₁H₄₆N₂O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₄₆N₂O₅

There total 16 articles about C₃₁H₄₆N₂O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C40H66N2O5Si (848731-54-4) → C31H46N2O5 (848731-62-4)

Guidance literature:

With tris(dimethylamino)sulfonium trimethylsilyldifluoride; In N,N-dimethyl acetamide; at 100 ℃;

DOI:10.1021/ol050038m

Reference yield:

C19H22N2O6S → C31H46N2O5 (848731-62-4)

Guidance literature:

Multi-step reaction with 15 steps

1.1: tetrahydrofuran; diethyl ether / -78 - -10 °C

2.1: 98 percent / KHMDS / tetrahydrofuran / -78 - 0 °C

3.1: aq. HF / acetonitrile / 20 °C

3.2: 87 percent / Et₃N / CH₂Cl₂ / -78 - 20 °C

4.1: 92 percent / 2,6-di-tert-butyl-4-methylpyridine; BCl₃ / CH₂Cl₂; heptane / 15 h / 20 °C

5.1: imidazole / acetonitrile

6.1: NaBH₄ / methanol

7.1: Et₃N / CH₂Cl₂

8.1: Na; naphthalene / 1,2-dimethoxy-ethane; tetrahydrofuran / -78 °C

9.1: NaBH₃CN; AcOH / acetonitrile / 20 °C

10.1: 75 percent / (PCy₃)2Cl₂Ru=CHPh / CH₂Cl₂ / 7 h / Heating

11.1: 93 percent / H₂ / Pd/C / ethyl acetate / 6 h / 20 °C

12.1: 83 percent / HCl / tetrahydrofuran; H₂O / 20 °C

13.1: 89 percent / NaHMDS / dimethylformamide / 20 °C

14.1: 85 percent / tris(dimethylamino)sulfur (trimethylsilyl)difluoride / N,N-dimethyl-acetamide / 100 °C

With 1H-imidazole; hydrogenchloride; sodium tetrahydroborate; 2,6-di-tert-butyl-4-methylpyridine; naphthalene; hydrogen fluoride; tris(dimethylamino)sulfonium trimethylsilyldifluoride; hydrogen; sodium hexamethyldisilazane; sodium; boron trichloride; potassium hexamethylsilazane; sodium cyanoborohydride; acetic acid; triethylamine; palladium on activated charcoal; Grubbs catalyst first generation; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; diethyl ether; n-heptane; dichloromethane; N,N-dimethyl acetamide; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; 1.1: Grignarg reaction / 2.1: Swern oxidation / 3.1: Wittig reaction;

DOI:10.1021/ol050038m

Reference yield:

C20H24N2O5S → C31H46N2O5 (848731-62-4)

Guidance literature:

Multi-step reaction with 16 steps

1.1: O₃; NaHCO₃ / CH₂Cl₂; methanol / -78 °C

1.2: 90 percent / Me₂S / -78 - 20 °C

2.1: tetrahydrofuran; diethyl ether / -78 - -10 °C

3.1: 98 percent / KHMDS / tetrahydrofuran / -78 - 0 °C

4.1: aq. HF / acetonitrile / 20 °C

4.2: 87 percent / Et₃N / CH₂Cl₂ / -78 - 20 °C

5.1: 92 percent / 2,6-di-tert-butyl-4-methylpyridine; BCl₃ / CH₂Cl₂; heptane / 15 h / 20 °C

6.1: imidazole / acetonitrile

7.1: NaBH₄ / methanol

8.1: Et₃N / CH₂Cl₂

9.1: Na; naphthalene / 1,2-dimethoxy-ethane; tetrahydrofuran / -78 °C

10.1: NaBH₃CN; AcOH / acetonitrile / 20 °C

11.1: 75 percent / (PCy₃)2Cl₂Ru=CHPh / CH₂Cl₂ / 7 h / Heating

12.1: 93 percent / H₂ / Pd/C / ethyl acetate / 6 h / 20 °C

13.1: 83 percent / HCl / tetrahydrofuran; H₂O / 20 °C

14.1: 89 percent / NaHMDS / dimethylformamide / 20 °C

15.1: 85 percent / tris(dimethylamino)sulfur (trimethylsilyl)difluoride / N,N-dimethyl-acetamide / 100 °C

With 1H-imidazole; hydrogenchloride; sodium tetrahydroborate; 2,6-di-tert-butyl-4-methylpyridine; naphthalene; hydrogen fluoride; tris(dimethylamino)sulfonium trimethylsilyldifluoride; hydrogen; sodium hexamethyldisilazane; sodium; boron trichloride; potassium hexamethylsilazane; sodium cyanoborohydride; sodium hydrogencarbonate; ozone; acetic acid; triethylamine; palladium on activated charcoal; Grubbs catalyst first generation; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; diethyl ether; n-heptane; dichloromethane; N,N-dimethyl acetamide; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; 2.1: Grignarg reaction / 3.1: Swern oxidation / 4.1: Wittig reaction;

DOI:10.1021/ol050038m

upstream raw materials:

C₄₀H₆₆N₂O₅Si

C₂₅H₃₂N₂O₆S

C₃₁H₄₆N₂O₆SSi

C₃₃H₆₂N₂O₄Si₂

Downstream raw materials:

C₃₈H₅₇IN₂O₄

C₃₈H₅₉IN₂O₄

C₃₀H₄₈N₂O₄