5-cyclopropyl-6-(cyclopropylmethoxy)nicotinic acid N′-(4-fluorophenyl)-N′-methylhydrazide

Base Information

Chemical Name:5-cyclopropyl-6-(cyclopropylmethoxy)nicotinic acid N′-(4-fluorophenyl)-N′-methylhydrazide
CAS No.:1427064-52-5
Molecular Formula:C₂₀H₂₂FN₃O₂
Molecular Weight:355.412
Hs Code.:

Synonyms:5-cyclopropyl-6-(cyclopropylmethoxy)nicotinic acid N′-(4-fluorophenyl)-N′-methylhydrazide

Suppliers and Price of 5-cyclopropyl-6-(cyclopropylmethoxy)nicotinic acid N′-(4-fluorophenyl)-N′-methylhydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-cyclopropyl-6-(cyclopropylmethoxy)nicotinic acid N′-(4-fluorophenyl)-N′-methylhydrazide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-cyclopropyl-6-(cyclopropylmethoxy)nicotinic acid N′-(4-fluorophenyl)-N′-methylhydrazide

There total 3 articles about 5-cyclopropyl-6-(cyclopropylmethoxy)nicotinic acid N′-(4-fluorophenyl)-N′-methylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1427064-97-8
5-cyclopropyl-6-cyclopropylmethoxy-nicotinic acid

: 1-(4-fluorophenyl)-1-methylhydrazine hydrochloride

: 1427064-52-5
5-cyclopropyl-6-(cyclopropylmethoxy)nicotinic acid N′-(4-fluorophenyl)-N′-methylhydrazide

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 1-(4-fluorophenyl)-1-methylhydrazine hydrochloride

: 1427064-97-8
5-cyclopropyl-6-cyclopropylmethoxy-nicotinic acid

: 1427064-52-5
5-cyclopropyl-6-(cyclopropylmethoxy)nicotinic acid N′-(4-fluorophenyl)-N′-methylhydrazide

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 912454-38-7
5-bromo-6-(cyclopropylmethoxy)-3-pyridinecarboxylic acid

: 1427064-52-5
5-cyclopropyl-6-(cyclopropylmethoxy)nicotinic acid N′-(4-fluorophenyl)-N′-methylhydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: caesium carbonate; palladium diacetate; catacxium A / toluene; water / 120 °C / Inert atmosphere

2: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide; tetrahydrofuran / 20 °C

With palladium diacetate; caesium carbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; catacxium A; In tetrahydrofuran; water; N,N-dimethyl-formamide; toluene;