{8-[bis-(4-chloro-phenyl)-hydroxy-methyl]-naphthalen-1-yl}-bis-(4-chloro-phenyl)-methanol

Base Information

• Chemical Name: {8-[bis-(4-chloro-phenyl)-hydroxy-methyl]-naphthalen-1-yl}-bis-(4-chloro-phenyl)-methanol
• CAS No.: 844692-70-2
• Molecular Formula: C₃₆H₂₄Cl₄O₂
• Molecular Weight: 630.397
• Mol file: 844692-70-2.mol

Synonyms:{8-[bis-(4-chloro-phenyl)-hydroxy-methyl]-naphthalen-1-yl}-bis-(4-chloro-phenyl)-methanol

Chemical Property of {8-[bis-(4-chloro-phenyl)-hydroxy-methyl]-naphthalen-1-yl}-bis-(4-chloro-phenyl)-methanol

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of {8-[bis-(4-chloro-phenyl)-hydroxy-methyl]-naphthalen-1-yl}-bis-(4-chloro-phenyl)-methanol

There total 1 articles about {8-[bis-(4-chloro-phenyl)-hydroxy-methyl]-naphthalen-1-yl}-bis-(4-chloro-phenyl)-methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

1,8-dilithionaphthalene*tmeda + 4,4'-Dichlorobenzophenone (90-98-2) → {8-[bis-(4-chloro-phenyl)-hydroxy-methyl]-naphthalen-1-yl}-bis-(4-chloro-phenyl)-methanol (844692-70-2)

Guidance literature:

In tetrahydrofuran; at -78 - 20 ℃; for 3h;

DOI:10.1021/ol0477071

Reference yield: 84.0%

{8-[bis-(4-chloro-phenyl)-hydroxy-methyl]-naphthalen-1-yl}-bis-(4-chloro-phenyl)-methanol (844692-70-2) → C36H22Cl4(2+)*2BF4(1-)

Guidance literature:

With tetrafluoroboric acid; trifluoroacetic anhydride; at 25 ℃; for 3h;

DOI:10.1021/ol0477071

Reference yield:

{8-[bis-(4-chloro-phenyl)-hydroxy-methyl]-naphthalen-1-yl}-bis-(4-chloro-phenyl)-methanol (844692-70-2) → 5-chloro-1,1,2,2-tetrakis-(4-chloro-phenyl)-acenaphthene

Guidance literature:

Multi-step reaction with 2 steps

1: 84 percent / aq. HBF₄; (CF₃CO)2O / 3 h / 25 °C

2: 90 percent / KCl; 18-crown-6 / acetonitrile / 1 h / 25 °C

With tetrafluoroboric acid; 18-crown-6 ether; potassium chloride; trifluoroacetic anhydride; In acetonitrile;

DOI:10.1021/ol0477071

upstream raw materials:

4,4'-Dichlorobenzophenone