Benzenesulfonamide, 4-amino-N-(4-iodo-5-methyl-3-isoxazolyl)-

Base Information

• Chemical Name: Benzenesulfonamide, 4-amino-N-(4-iodo-5-methyl-3-isoxazolyl)-
• CAS No.: 1024-37-9
• Molecular Formula: C₁₀H₁₀IN₃O₃S
• Molecular Weight: 379.178
• DSSTox Substance ID: DTXSID70907476
• Nikkaji Number: J325.845I
• Wikidata: Q82876518
• ChEMBL ID: CHEMBL298976
• Mol file: 1024-37-9.mol

Synonyms:Sulfiodizole;1024-37-9;Benzenesulfonamide, 4-amino-N-(4-iodo-5-methyl-3-isoxazolyl)-;BRN 0808571;CHEMBL298976;4-Iodo-5-methyl-3-sulfanilamidoisoxazole;Sulfanilamide, N(sup 1)-(4-iodo-5-methyl-3-isoxazolyl)-;DTXSID70907476;BDBM50091532;LS-147799;4-Amino-N-(4-iodo-5-methylisoxazol-3-yl)benzenesulfonamide;4-Amino-N-(4-iodo-5-methyl-isoxazol-3-yl)-benzenesulfonamide;4-Amino-N-(4-iodo-5-methyl-1,2-oxazol-3-yl)benzene-1-sulfonamide

Chemical Property of Benzenesulfonamide, 4-amino-N-(4-iodo-5-methyl-3-isoxazolyl)-

Chemical Property:

• Vapor Pressure: 3.7E-11mmHg at 25°C
• Boiling Point: 526.1°C at 760 mmHg
• Flash Point: 272°C
• Density: 1.942g/cm³
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 378.94876
• Heavy Atom Count: 18
• Complexity: 378

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=NO1)NS(=O)(=O)C2=CC=C(C=C2)N)I

Technology Process of Benzenesulfonamide, 4-amino-N-(4-iodo-5-methyl-3-isoxazolyl)-

There total 3 articles about Benzenesulfonamide, 4-amino-N-(4-iodo-5-methyl-3-isoxazolyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(4-iodo-5-methyl-isoxazol-3-yl)-4-nitro-benzenesulfonamide (6453-55-0) → Sulfiodizole (1024-37-9)

Guidance literature:

With hydrogen; platinum; In ethanol; ethyl acetate; for 3h; Ambient temperature;

DOI:10.1248/cpb.14.280

Reference yield:

N-(5-methyl-isoxazol-3-yl)-4-nitro-benzenesulfonamide (29699-89-6) → Sulfiodizole (1024-37-9)

Guidance literature:

Multi-step reaction with 2 steps

1: ICl / dimethylformamide / 2 h / 50 °C

2: H₂ / Pt / ethyl acetate; ethanol / 3 h / Ambient temperature

With hydrogen; Iodine monochloride; platinum; In ethanol; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1248/cpb.14.280

Reference yield:

→ Sulfiodizole (1024-37-9)

Guidance literature:

p-Acetylaminobenzosulfonylchlorid, entspr. Isoxazol/NaOH;

upstream raw materials:

N-(4-iodo-5-methyl-isoxazol-3-yl)-4-nitro-benzenesulfonamide

N-(5-methyl-isoxazol-3-yl)-4-nitro-benzenesulfonamide