cyclopentyl N-[(5E)-6-(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3,5-difluorophenyl)hex-5-enoyl]-L-leucinate

Base Information

Chemical Name:cyclopentyl N-[(5E)-6-(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3,5-difluorophenyl)hex-5-enoyl]-L-leucinate
CAS No.:1021853-18-8
Molecular Formula:C₃₇H₅₀F₂N₆O₄
Molecular Weight:680.839
Hs Code.:

Synonyms:cyclopentyl N-[(5E)-6-(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3,5-difluorophenyl)hex-5-enoyl]-L-leucinate

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Chemical Property of cyclopentyl N-[(5E)-6-(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3,5-difluorophenyl)hex-5-enoyl]-L-leucinate

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Technology Process of cyclopentyl N-[(5E)-6-(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3,5-difluorophenyl)hex-5-enoyl]-L-leucinate

There total 1 articles about cyclopentyl N-[(5E)-6-(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3,5-difluorophenyl)hex-5-enoyl]-L-leucinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1021853-18-8
cyclopentyl N-[(5E)-6-(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3,5-difluorophenyl)hex-5-enoyl]-L-leucinate

Guidance literature:

Reference yield: 8.4%

: 1021853-59-7
(7R)-2-[(4-bromo-2-fluorophenyl)amino]-8-cyclopentyl-7-ethyl-5-methyl-7,8-dihydropteridin-6(5h)-one

: 1021853-18-8
cyclopentyl N-[(5E)-6-(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3,5-difluorophenyl)hex-5-enoyl]-L-leucinate

: 1021853-16-6
cyclopentyl N-[(5E)-6-(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-fluorophenyl)hex-5-enoyl]-L-leucinate

Guidance literature:: With tetrabutylammomium bromide; triethylamine; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In N,N-dimethyl-formamide; at 130 ℃; for 8h; Microwave irradiation;