Technology Process of 47-(Dioxolan-2-yl)heptatetraconta-12,24,36-trienyl(triphenyl)phosphonium bromide
There total 21 articles about 47-(Dioxolan-2-yl)heptatetraconta-12,24,36-trienyl(triphenyl)phosphonium bromide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
various solvent(s);
for 41h;
Heating;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: Ph3P / 480 h / 102.5 - 103.5 °C
2: p-TsOH / CH2Cl2 / Heating
3: K2CO3 / 18-crown-6
4: 672 h / 102.5 - 103.5 °C
5: 1.) KH / 1.) 18-crown-6 / 1.) THF, 55 deg C, 48 h, 2.) heating, 2 h
6: tetrabutylammonium bromide / various solvent(s) / 42 h / Heating
7: 75 percent / 2,2-dimethyl-1,3-dioxolane / acetonitrile / 112 h / Heating
With
2,2-dimethyl-1,3-dioxolane; tetrabutylammomium bromide; potassium hydride; potassium carbonate; toluene-4-sulfonic acid; triphenylphosphine;
18-crown-6 ether;
In
dichloromethane; acetonitrile;
DOI:10.1039/p19960001635
- Guidance literature:
-
Multi-step reaction with 6 steps
1: Swern oxidation
2: K2CO3 / 18-crown-6
3: 672 h / 102.5 - 103.5 °C
4: 1.) KH / 1.) 18-crown-6 / 1.) THF, 55 deg C, 48 h, 2.) heating, 2 h
5: tetrabutylammonium bromide / various solvent(s) / 42 h / Heating
6: 75 percent / 2,2-dimethyl-1,3-dioxolane / acetonitrile / 112 h / Heating
With
2,2-dimethyl-1,3-dioxolane; tetrabutylammomium bromide; potassium hydride; potassium carbonate;
18-crown-6 ether;
In
acetonitrile;
DOI:10.1039/p19960001635