(E)-2-Hydroxy-2-methylpropanoic acid (1-(2-chlorophenyl)-2-hydroxyethylidene)hydrazide

Base Information

• Chemical Name: (E)-2-Hydroxy-2-methylpropanoic acid (1-(2-chlorophenyl)-2-hydroxyethylidene)hydrazide
• CAS No.: 133662-06-3
• Molecular Formula: C₁₂H₁₅ClN₂O₃
• Molecular Weight: 270.716
• Mol file: 133662-06-3.mol

Synonyms:BRN 4258341;(E)-2-Hydroxy-2-methylpropanoic acid (1-(2-chlorophenyl)-2-hydroxyethylidene)hydrazide;Propanoic acid, 2-hydroxy-2-methyl-, (1-(2-chlorophenyl)-2-hydroxyethylidene)hydrazide, (E)-;133662-06-3;LS-121488

Chemical Property of (E)-2-Hydroxy-2-methylpropanoic acid (1-(2-chlorophenyl)-2-hydroxyethylidene)hydrazide

Chemical Property:

• XLogP3: 1.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 270.0771200
• Heavy Atom Count: 18
• Complexity: 331

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C(=O)NN=C(CO)C1=CC=CC=C1Cl)O
• Isomeric SMILES: CC(C)(C(=O)N/N=C(/CO)\C1=CC=CC=C1Cl)O

Technology Process of (E)-2-Hydroxy-2-methylpropanoic acid (1-(2-chlorophenyl)-2-hydroxyethylidene)hydrazide

There total 1 articles about (E)-2-Hydroxy-2-methylpropanoic acid (1-(2-chlorophenyl)-2-hydroxyethylidene)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

2-hydroxy-2-methylpropionohydrazide (42596-46-3) + 1-(2-chlorophenyl)-2-hydroxyethanone (133662-20-1) → 2-Hydroxy-2-methyl-propionic acid [1-(2-chloro-phenyl)-2-hydroxy-eth-(Z)-ylidene]-hydrazide (133662-06-3,133662-62-1)

Guidance literature:

In ethanol; for 4h; Heating;

DOI:10.1016/0223-5234(90)90198-C

upstream raw materials:

2-hydroxy-2-methylpropionohydrazide

1-(2-chlorophenyl)-2-hydroxyethanone