C₁₃H₁₂O₄

Base Information

• Chemical Name: C₁₃H₁₂O₄
• CAS No.: 1289031-39-5
• Molecular Formula: C₁₃H₁₂O₄
• Molecular Weight: 232.236
• Mol file: 1289031-39-5.mol

Synonyms:C₁₃H₁₂O₄

Chemical Property of C₁₃H₁₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₃H₁₂O₄

There total 1 articles about C₁₃H₁₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

methyl-5-formyl-2-hydroxybenzoate (41489-76-3) + 3-butyn-1-yl p-toluenesulfonate (23418-85-1) → C13H12O4 (1289031-39-5)

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 80 ℃; for 12h; Inert atmosphere;

DOI:10.1021/jo102577a

Reference yield: 100.0%

C13H12O4 (1289031-39-5) → C12H10O4 (1289031-41-9)

Guidance literature:

With lithium hydroxide monohydrate; In tetrahydrofuran; methanol; water; at 20 ℃; for 4h;

DOI:10.1021/jo102577a

Reference yield:

C13H12O4 (1289031-39-5) → C39H56N2O7 (1289031-44-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: lithium hydroxide monohydrate / tetrahydrofuran; methanol; water / 4 h / 20 °C

2.1: triethylamine; isobutyl chloroformate / chloroform / 20 °C / Inert atmosphere; Cooling with ice

2.2: 48 h / 20 °C / Inert atmosphere

With lithium hydroxide monohydrate; triethylamine; isobutyl chloroformate; In tetrahydrofuran; methanol; chloroform; water;

DOI:10.1021/jo102577a

upstream raw materials:

methyl-5-formyl-2-hydroxybenzoate

3-butyn-1-yl p-toluenesulfonate

Downstream raw materials:

C₁₂H₁₀O₄

C₃₉H₅₆N₂O₇