1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride

Base Information

Chemical Name:1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride
CAS No.:102417-86-7
Molecular Formula:C₁₃H₁₇N
Molecular Weight:187.285
Hs Code.:
European Community (EC) Number:634-400-7
ChEMBL ID:CHEMBL536788
Mol file:102417-86-7.mol

Synonyms:1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride;2'-Methyl-MPTP hydrochloride;1-methyl-4-(2-methylphenyl)-3,6-dihydro-2H-pyridine;hydrochloride;CHEMBL536788;SCHEMBL2263936;MFCD00055222;127382-79-0;J-000683;2-METHYL MPTP HYDROCHLORIDE DOPAMINERGI C NEUROTOX;1-Methyl-4-(o-tolyl)-1,2,3,6-tetrahydropyridine hydrochloride;1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride, solid

Suppliers and Price of 1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Methyl-4-(2’-methylphenyl)-1,2,3,6-tetrahydropyridine
10mg
$ 215.00

Sigma-Aldrich
1-Methyl-4-(2′-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride solid
10mg
$ 285.00

American Custom Chemicals Corporation
1-METHYL-4-(2'-METHYLPHENYL)-1,2,3,6-TETRAHYDROPYRIDINE 95.00%
5MG
$ 504.52

Total 2 raw suppliers

Chemical Property of 1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride

Chemical Property:

Boiling Point:288.5°Cat760mmHg
Flash Point:117.2°C
PSA：3.24000
Density:0.989g/cm³
LogP:2.65180
Solubility.:H2O: soluble
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:223.1127773
Heavy Atom Count:15
Complexity:219

Purity/Quality:

97% ^*data from raw suppliers

1-Methyl-4-(2’-methylphenyl)-1,2,3,6-tetrahydropyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25-39/23/24/25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C2=CCN(CC2)C.Cl

Technology Process of 1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride

There total 3 articles about 1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 127382-78-9
4-hydroxy-1-methyl-4-(2-methylphenyl)piperidine

: 102417-86-7
1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine

Guidance literature:: With hydrogenchloride; acetic acid; for 10h; Heating;
DOI:10.1021/jm00170a029

Reference yield:

: 1445-73-4
1-Methyl-4-piperidone

: 102417-86-7
1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) diethyl ether, hexane, -78 deg C, 30 min, 2.) RT, 1 h

2: HCl, acetic acid / 10 h / Heating

With hydrogenchloride; n-butyllithium; acetic acid;
DOI:10.1021/jm00170a029

Reference yield:

: 95-46-5
2-methylphenyl bromide

: 102417-86-7
1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) n-BuLi / 1.) diethyl ether, hexane, -78 deg C, 30 min, 2.) RT, 1 h

2: HCl, acetic acid / 10 h / Heating

With hydrogenchloride; n-butyllithium; acetic acid;
DOI:10.1021/jm00170a029